DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drak and dapk2a

DIOPT Version :9

Sequence 1:	NP_001162723.1	Gene:	Drak / 32097	FlyBaseID:	FBgn0052666	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001116536.2	Gene:	dapk2a / 571352	ZFINID:	ZDB-GENE-080402-8	Length:	484	Species:	Danio rerio

Alignment Length:	325	Identity:	119/325 - (36%)
Similarity:	188/325 - (57%)	Gaps:	29/325 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 INEIYEVEQTPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSS----DKEIKHEIAVLMLCE 92
            :.:.:|:.: ....|:||.|::...|::|..|||||:|:|:...|.    .:||:.|:.:|....
Zfish     9 VEDFFEIGE-ELGSGQFAIVKQCREKSSGRDFAAKFIKKRQSNASRRGVLREEIEREVNILQQIH 72

  Fly    93 GEDNIVNLNAVHETRSDTALLLELATGGELQTILDNEECLTEAQARHCMREVLKALKFLHDRSIA 157
             ..|||.|:.|.|.::|..|:|||.:||||...|..:|.|:|.:|...::::|:.:.:||.|:||
Zfish    73 -HPNIVMLHDVFENKTDVVLILELVSGGELFDFLAQKESLSEEEATQFIKQILEGVHYLHSRNIA 136

  Fly   158 HLDLKPQNILLAGERIE-DGLKLCDFGISRVVCEGINVREMAGTPDYVAPEVLQYEPLSLLTDIW 221
            |.||||:||:|..:... ..:||.|||::..:.||:..:.:.|||::||||::.||||.|..|:|
Zfish   137 HFDLKPENIMLLDKNAPLPRIKLIDFGLAHKIAEGVEFKNIFGTPEFVAPEIVNYEPLGLEADMW 201

  Fly   222 SVGVLTYVLLSGFSPFGGDTKQETFLNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPNDRMNA 286
            ||||:||:||||.|||.|:|||:|..|||.....|.|..||..|.:|.:|||:.|......|:..
Zfish   202 SVGVITYILLSGASPFLGETKQDTLGNISAMNYEFDDEFFGHTSELAKNFIRQLLEKDTKKRLTI 266

  Fly   287 TGCLDHIWLKDDCSLDRQIYLQPQSDAEEEEEEDVDDDVEDEEEEEQVEEEEEETQNVEEPTTEA 351
            ...|:|.|:|.:                 |.:||.:...|.:.|..|:     :|:.::|.|.::
Zfish   267 QDALNHAWIKSN-----------------EHKEDRNKAPERKRERRQL-----KTKRLKEYTIKS 309

Fly 352 351
Zfish 310 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drak	NP_001162723.1	STKc_DRAK	28..295	CDD:271008	108/267 (40%)
		S_TKc	45..295	CDD:214567	107/254 (42%)
		PHA03255	379..>554	CDD:165513
dapk2a	NP_001116536.2	PKc_like	7..275	CDD:304357	108/267 (40%)
dapk2a	NP_001116536.2	S_TKc	13..275	CDD:214567	108/263 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910