DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drak and mylk4b

DIOPT Version :9

Sequence 1:	NP_001162723.1	Gene:	Drak / 32097	FlyBaseID:	FBgn0052666	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	XP_021324306.1	Gene:	mylk4b / 449707	ZFINID:	ZDB-GENE-041001-128	Length:	697	Species:	Danio rerio

Alignment Length:	268	Identity:	101/268 - (37%)
Similarity:	151/268 - (56%)	Gaps:	6/268 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 INEIYEV-EQTPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSSDKEIKHEIAVLMLCEGED 95
            |...|.: ::.....|:|..|.:...|::|...|||.:|  .|:|...:.:|.||.|:... ...
Zfish   410 ITSYYNINKEEVLGGGRFGIVHKCEEKSSGLILAAKIIK--ARSQKEKEVVKCEIEVMNQL-NHA 471

  Fly    96 NIVNLNAVHETRSDTALLLELATGGEL-QTILDNEECLTEAQARHCMREVLKALKFLHDRSIAHL 159
            |::.|.|..|:|.:..|::|...|||| :.|:|....|||......:|::.:.|:::|...|.||
Zfish   472 NLIQLYAAFESRHEITLVMEYVDGGELFERIIDENYKLTELDTVLFIRQITEGLQYMHKMYILHL 536

  Fly   160 DLKPQNILLAGERIEDGLKLCDFGISRVVCEGINVREMAGTPDYVAPEVLQYEPLSLLTDIWSVG 224
            ||||:|||.. .|..:.:|:.|||::|.......:|...|||:::||||:.||.:|..||:||:|
Zfish   537 DLKPENILCI-SRETNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFPTDMWSLG 600

  Fly   225 VLTYVLLSGFSPFGGDTKQETFLNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPNDRMNATGC 289
            |:||:||||.|||.|:...||..||..|..:|.:..|..:|..|.|||.|.|....:.||:|:..
Zfish   601 VITYMLLSGLSPFLGEDDNETLNNILACQWSFEEAEFADISEEAKDFISRLLVKSKSWRMSASQS 665

  Fly   290 LDHIWLKD 297
            |.|.||.|
Zfish   666 LKHPWLSD 673

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drak	NP_001162723.1	STKc_DRAK	28..295	CDD:271008	98/264 (37%)
		S_TKc	45..295	CDD:214567	96/250 (38%)
		PHA03255	379..>554	CDD:165513
mylk4b	XP_021324306.1	STKc_MLCK4	411..671	CDD:271095	97/263 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910