DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drak and Camk1d

DIOPT Version :9

Sequence 1:	NP_001162723.1	Gene:	Drak / 32097	FlyBaseID:	FBgn0052666	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001100835.1	Gene:	Camk1d / 307124	RGDID:	1560691	Length:	385	Species:	Rattus norvegicus

Alignment Length:	276	Identity:	96/276 - (34%)
Similarity:	148/276 - (53%)	Gaps:	3/276 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 DINEIYEVEQTPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSSDKEIKHEIAVLMLCEGED 95
            ||.:|:|.::| ...|.|:.|..|..|.||..||.|.:. ::..:..:..|::|||||...:.|
  Rat    18 DIKKIFEFKET-LGTGAFSEVVLAEEKATGKLFAVKCIP-KKALKGKESSIENEIAVLRKIKHE- 79

  Fly    96 NIVNLNAVHETRSDTALLLELATGGELQTILDNEECLTEAQARHCMREVLKALKFLHDRSIAHLD 160
            |||.|..::|:.:...|:::|.:||||...:..:...||..|...:|:||.|:.:||...|.|.|
  Rat    80 NIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRD 144

  Fly   161 LKPQNILLAGERIEDGLKLCDFGISRVVCEGINVREMAGTPDYVAPEVLQYEPLSLLTDIWSVGV 225
            |||:|:|...:..|..:.:.|||:|::..:|..:....|||.|||||||..:|.|...|.||:||
  Rat   145 LKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGV 209

  Fly   226 LTYVLLSGFSPFGGDTKQETFLNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPNDRMNATGCL 290
            :.|:||.|:.||..:...:.|..|.:....|....:..:|..|.||||..:...||.|.......
  Rat   210 IAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAA 274

  Fly   291 DHIWLKDDCSLDRQIY 306
            .|.|:..|.:|.:.|:
  Rat   275 RHPWIAGDTALSKNIH 290

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drak	NP_001162723.1	STKc_DRAK	28..295	CDD:271008	92/263 (35%)
		S_TKc	45..295	CDD:214567	87/249 (35%)
		PHA03255	379..>554	CDD:165513
Camk1d	NP_001100835.1	STKc_CaMKI_delta	12..312	CDD:271070	96/276 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910