DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drak and Mylk3

DIOPT Version :9

Sequence 1:	NP_001162723.1	Gene:	Drak / 32097	FlyBaseID:	FBgn0052666	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001104280.1	Gene:	Mylk3 / 291926	RGDID:	1305801	Length:	786	Species:	Rattus norvegicus

Alignment Length:	295	Identity:	107/295 - (36%)
Similarity:	157/295 - (53%)	Gaps:	16/295 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LVSCPD--INEIYEVEQ-TPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSSDKEIKHEIAV 87
            :||..|  |:..|.|.| .....|:|..|.|...::||...|||.:|.:......|  :|:||.:
  Rat   468 VVSIKDTLISTSYTVSQHEVLGGGRFGQVHRCTERSTGLALAAKIIKVKNIKDRED--VKNEINI 530

  Fly    88 LMLCEGEDNIVNLNAVHETRSDTALLLELATGGEL-QTILDNEECLTEAQARHCMREVLKALKFL 151
            :... ...|::.|....|:::...|::|...|||| ..|.|.:..|||.......|::.:.:.:|
  Rat   531 MNQL-SHVNLIQLYDAFESKNSFTLIMEYVDGGELFDRITDEKYHLTELDVVLFTRQICEGVHYL 594

  Fly   152 HDRSIAHLDLKPQNILLAGERIEDGLKLCDFGISRVVCEGINVREMAGTPDYVAPEVLQYEPLSL 216
            |...|.||||||:|||...:.... :|:.|||::|.......::...|||:::||||:.||.:|.
  Rat   595 HQHYILHLDLKPENILCVSQTGHQ-IKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYEFVSF 658

  Fly   217 LTDIWSVGVLTYVLLSGFSPFGGDTKQETFLNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPN 281
            .||:|||||:||:||||.|||.|:|..||...|..|:..|..:.|.|:|..|.||:.|.|..:.:
  Rat   659 PTDMWSVGVITYMLLSGLSPFLGETDAETMNFIVNCSWDFDADTFKGLSEEAKDFVSRLLVKEKS 723

  Fly   282 DRMNATGCLDHIWLK--------DDCSLDRQIYLQ 308
            .||:||.||.|.||.        .:..|..|:.||
  Rat   724 CRMSATQCLKHEWLNHLIAKASGSNVRLRSQLLLQ 758

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drak	NP_001162723.1	STKc_DRAK	28..295	CDD:271008	100/270 (37%)
		S_TKc	45..295	CDD:214567	94/250 (38%)
		PHA03255	379..>554	CDD:165513
Mylk3	NP_001104280.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	233..258
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	279..315
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	333..443
		STKc_MLCK3	477..737	CDD:271094	97/263 (37%)
		S_TKc	485..737	CDD:214567	94/255 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910