DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drak and Dclk3

DIOPT Version :9

Sequence 1:	NP_001162723.1	Gene:	Drak / 32097	FlyBaseID:	FBgn0052666	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_766516.2	Gene:	Dclk3 / 245038	MGIID:	3039580	Length:	790	Species:	Mus musculus

Alignment Length:	284	Identity:	94/284 - (33%)
Similarity:	150/284 - (52%)	Gaps:	20/284 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 RLKGLLVSCPDINEIYEVEQTPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSSDKE--IKH 83
            |.||::.:  |:.:.|::... ...|.||.|:...|:.|...:|.|.:.   ::|...||  :..
Mouse   501 RPKGIISA--DVEKHYDIGGV-IGDGNFATVKECRHRETKQAYAMKMID---KSQLKGKEDIVDS 559

  Fly    84 EIAVLMLCEGEDNIVNLNAVHETRSDTALLLELATGGEL-QTILDNEECLTEAQARHCMREVLKA 147
            ||.::... ...|||.|:.|:||.::..|::|...||:| ..|::|.: ..|.:|...:.::.||
Mouse   560 EILIIQSL-SHPNIVKLHEVYETEAEIYLIMEYVQGGDLFDAIVENVK-FPEPEAAVMITDLCKA 622

  Fly   148 LKFLHDRSIAHLDLKPQNILLAGERIED---GLKLCDFGISRVVCEGINVREMAGTPDYVAPEVL 209
            |..:||::|.|.|:||:|:|:  :|.||   .|||.|||:::.|...|..  :.|||.|||||:|
Mouse   623 LVHMHDKNIVHRDVKPENLLV--QRNEDKSITLKLADFGLAKYVVRPIFT--VCGTPTYVAPEIL 683

  Fly   210 QYEPLSLLTDIWSVGVLTYVLLSGFSPF-GGDTKQETFLNISQCA-LTFPDNLFGGVSPVAIDFI 272
            ..:...|..|:|:.||:.|:||.||.|| ..:..|:...||.|.. ..|....:..:|..|.|.:
Mouse   684 SEKGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQVGQFEFLSPYWDNISDAAKDLV 748

  Fly   273 RRALRIKPNDRMNATGCLDHIWLK 296
            |..|.:.|..|..|...|.|.|::
Mouse   749 RNLLEVDPKKRYTAEQVLQHPWIE 772

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drak	NP_001162723.1	STKc_DRAK	28..295	CDD:271008	90/274 (33%)
		S_TKc	45..295	CDD:214567	88/257 (34%)
		PHA03255	379..>554	CDD:165513
Dclk3	NP_766516.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
		UBQ	92..177	CDD:294102
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	201..290
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	315..506		3/4 (75%)
		PKc_like	513..770	CDD:304357	89/266 (33%)
		S_TKc	514..771	CDD:214567	89/266 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910