DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drak and Mylk4

DIOPT Version :9

Sequence 1:	NP_001162723.1	Gene:	Drak / 32097	FlyBaseID:	FBgn0052666	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	XP_006516731.1	Gene:	Mylk4 / 238564	MGIID:	3643758	Length:	656	Species:	Mus musculus

Alignment Length:	311	Identity:	108/311 - (34%)
Similarity:	164/311 - (52%)	Gaps:	28/311 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 IGDGLLD-VDADRLKGLLVSCPDI-------------------NEIYEVEQTP-FARGKFAAVRR 53
            :||.|.| :...|.:.|.|...||                   :.:|.|.::. ...|:|..|.:
Mouse   328 LGDRLQDGMTTSREQDLEVPLDDIPAPAAPFDHRMVMAKHASVDNLYTVSKSEILGGGRFGQVHK 392

  Fly    54 AIHKNTGSHFAAKFLKRRRRAQSSDKE-IKHEIAVLMLCEGEDNIVNLNAVHETRSDTALLLELA 117
            ...|.||...|||.:|.|   .:.||| :|:||:|:...: ..|::.|....|::.|..|::|..
Mouse   393 CEEKATGLKLAAKIIKTR---GAKDKEDVKNEISVMNQLD-HVNLIQLYDAFESKHDIILVMEYV 453

  Fly   118 TGGELQTILDNEEC-LTEAQARHCMREVLKALKFLHDRSIAHLDLKPQNILLAGERIEDGLKLCD 181
            .||||...:.:|.| |||......|:::.:.::::|...|.||||||:|||.. .|....:|:.|
Mouse   454 EGGELFDRIIDENCNLTELDTILFMKQICEGIRYMHQMYILHLDLKPENILCV-NRDAKQIKIID 517

  Fly   182 FGISRVVCEGINVREMAGTPDYVAPEVLQYEPLSLLTDIWSVGVLTYVLLSGFSPFGGDTKQETF 246
            ||::|.......::...|||:::||||:.|:.:|..||:|||||:||:||||.|||.||...||.
Mouse   518 FGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFSTDMWSVGVITYMLLSGLSPFLGDNDAETL 582

  Fly   247 LNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPNDRMNATGCLDHIWLKD 297
            .||..|.....|..|..:|..|.:||.:.|..:.:.|::|:..|.|.||.|
Mouse   583 TNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSD 633

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drak	NP_001162723.1	STKc_DRAK	28..295	CDD:271008	98/288 (34%)
		S_TKc	45..295	CDD:214567	94/251 (37%)
		PHA03255	379..>554	CDD:165513
Mylk4	XP_006516731.1	STKc_MLCK4	371..631	CDD:271095	96/264 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910