Protein Alignment Drak and Mylk2

DIOPT Version :10

• Sequence 1: NP_996411.2
• Gene: Drak / 32097
• FlyBaseID: FBgn0052666
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_001074513.2
• Gene: Mylk2 / 228785
• MGIID: 2139434
• Length: 613
• Species: Mus musculus
• Alignment Length: 261
• Identity: 95/261 - (36%)
• Similarity: 138/261 - (52%)
• Gaps: 21/261 - (8%)

  Fly    46 GKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSSDKEIKHEIAVLMLCE-----GEDNIVNLNAVHE 105
            |||.||.....:.||...|||.:|::   ...|||:     ||:..|     ...|::.|.|..|
Mouse   311 GKFGAVCTCTERATGLKLAAKVIKKQ---TPKDKEM-----VLLEIEVMNQLNHRNLIQLYAAIE 367

  Fly   106 TRSDTALLLELATGGEL-QTILDNEECLTEAQARHCMREVLKALKFLHDRSIAHLDLKPQNIL-- 167
            |..:..|.:|...|||| :.|:|.:..|||......:|::...:.|:|...:.||||||:|||
Mouse   368 TSHEIILFMEYIEGGELFERIVDEDYHLTEVDTMVFVRQICDGILFMHKMRVLHLDLKPENILCV 432

  Fly   168 -LAGERIEDGLKLCDFGISRVVCEGINVREMAGTPDYVAPEVLQYEPLSLLTDIWSVGVLTYVLL 231
             ..|..:    |:.|||::|.......::...|||::::|||:.|:.:|..||:||:||:||:||
Mouse   433 NTTGHLV----KIIDFGLARRYNPNEKLKVNFGTPEFLSPEVVNYDQISDKTDMWSLGVITYMLL 493

  Fly   232 SGFSPFGGDTKQETFLNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPNDRMNATGCLDHIWLK 296
            ||.|||.||...||..|:......|.:..|..||..|.||:...|....:.||:|..||.|.||.
Mouse   494 SGLSPFLGDDDTETLNNVLSANWYFDEETFEAVSDEAKDFVSNLLTKDQSARMSAEQCLAHPWLN 558

  Fly   297 D 297
            :
Mouse   559 N 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drak	NP_996411.2	STKc_DRAK	28..295	CDD:271008	93/257 (36%)
		PHA03255	379..>554	CDD:165513
Mylk2	NP_001074513.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..168
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	219..240
		STKc_MLCK2	298..557	CDD:271092	93/257 (36%)
		Calmodulin-binding. /evidence=ECO:0000250	591..603