DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Drak and Dapk3

DIOPT Version :9

Sequence 1:	NP_001162723.1	Gene:	Drak / 32097	FlyBaseID:	FBgn0052666	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001177403.2	Gene:	Dapk3 / 13144	MGIID:	1203520	Length:	465	Species:	Mus musculus

Alignment Length:	275	Identity:	119/275 - (43%)
Similarity:	167/275 - (60%)	Gaps:	15/275 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 DINEIYEVEQTPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQS----SDKEIKHEIAVLMLC 91
            |:.:.||:.: ....|:||.||:...|.||..:||||:|:||...|    |.:||:.|:::|...
Mouse    25 DVEDHYEMGE-ELGSGQFAIVRKCQQKGTGMEYAAKFIKKRRLPSSRRGVSREEIEREVSILREI 88

  Fly    92 EGEDNIVNLNAVHETRSDTALLLELATGGELQTILDNEECLTEAQARHCMREVLKALKFLHDRSI 156
            . ..||:.|:.|.|.::|..|:|||.:||||...|..:|.|||.:|...::::|..:.:||.:.|
Mouse    89 R-HPNIITLHDVFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVHYLHSKRI 152

  Fly   157 AHLDLKPQNILL-----AGERIEDGLKLCDFGISRVVCEGINVREMAGTPDYVAPEVLQYEPLSL 216
            ||.||||:||:|     |..||    ||.||||:..:..|...:.:.|||::||||::.||||.|
Mouse   153 AHFDLKPENIMLLDKHAASPRI----KLIDFGIAHRIEAGSEFKNIFGTPEFVAPEIVNYEPLGL 213

  Fly   217 LTDIWSVGVLTYVLLSGFSPFGGDTKQETFLNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPN 281
            ..|:||:||:||:||||.|||.|:|||||..|||.....|.:..|...|.:|.|||||.|...|.
Mouse   214 EADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYFSSTSELAKDFIRRLLVKDPK 278

  Fly   282 DRMNATGCLDHIWLK 296
            .||.....|:|.|:|
Mouse   279 RRMTIAQSLEHSWIK 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Drak	NP_001162723.1	STKc_DRAK	28..295	CDD:271008	117/272 (43%)
		S_TKc	45..295	CDD:214567	114/258 (44%)
		PHA03255	379..>554	CDD:165513
Dapk3	NP_001177403.2	STKc_DAPK	24..292	CDD:271007	117/272 (43%)
Dapk3	NP_001177403.2	S_TKc	30..292	CDD:214567	116/267 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	222	1.000	Domainoid score	I2576
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm42858
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910