Protein Alignment Drak and Drak

DIOPT Version :10

• Sequence 1: NP_996411.2
• Gene: Drak / 32097
• FlyBaseID: FBgn0052666
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_311247.6
• Gene: Drak / 1272302
• VectorBaseID: AGAMI1_004265
• Length: 769
• Species: Anopheles gambiae
• Alignment Length: 689
• Identity: 253/689 - (36%)
• Similarity: 331/689 - (48%)
• Gaps: 201/689 - (29%)

  Fly     5 KGIFPIGDGLLDVDADRLKGLLVSCP-DINEIYEVEQTPFARGKFAAVRRAIHKNTGSHFAAKFL 68
            :|...:|||.|.:..::|..|  ..| ||.|:|.||:|..|:|.:..||.||.|.:|..:|||||
Mosquito     6 EGFSHVGDGRLSIGEEQLAKL--KTPRDIGEVYLVEETWIAKGMYGIVRSAISKQSGISYAAKFL 68

  Fly    69 KRRRRAQSSDKEIKHEIAVLMLCEGEDNIVNLNAVHETRSDTALLLELATGGELQTILDNEECLT 133
            :||||.|....||.|||||||||...|::|.|.|||||||:.||:|||||||||||::|.:..|:
Mosquito    69 RRRRRGQCCLNEINHEIAVLMLCADSDHVVKLQAVHETRSEIALILELATGGELQTLIDEQGHLS 133

  Fly   134 EAQARHCMREVLKALKFLHDRSIAHLDLKPQNILLAGERIEDGLKLCDFGISRVVCEGINVREMA 198
            |.:.|.||||:|:||:.:|.:||||||||||||||||:.::||||||||||:|.:.|...:.|:.
Mosquito   134 EQKTRVCMREILRALQHMHSKSIAHLDLKPQNILLAGKTVDDGLKLCDFGIARFIAEKNKIYEIV 198

  Fly   199 GTPDYVAPEVLQYEPLSLLTDIWSVGVLTYVLLSGFSPFGGDTKQETFLNISQCALTFPDNLFGG 263
            |||||||||||.|:||||.|||||:||:.||||:|.||||||:|||||||:::|:|||||.||.|
Mosquito   199 GTPDYVAPEVLHYDPLSLQTDIWSIGVVAYVLLTGLSPFGGDSKQETFLNVTKCSLTFPDELFDG 263

  Fly   264 VSPVAIDFIRRALRIKPNDRMNATGCLDHIWLKDDCSLDRQIYLQPQSDAEEE----EEEDV--- 321
            :|..|||||:.||||||.:|:....||:|.|||:.....|:..|..::.....    .|.|.
Mosquito   264 ISSDAIDFIKSALRIKPKERLTVDECLEHRWLKEKTVCLREELLAARATLSRNGTGIGEWDYSKT 328

  Fly   322 -------DDDVEDEEEEEQ----------------VEEEEEETQNVEEPTTEAPQQQQQPVQQHQ 363
                   ||.:.:..|...                :|.......||..|.....:|     |||.
Mosquito   329 TTTTLMGDDALLNGCEPTNGDGGGGGGGGGGGALVLENGSSNGCNVVRPHEAGTKQ-----QQHM 388

  Fly   364 LA---KSGQI----HSKPTHN------GHHRANSGGSISKIPIATSKLQSTPSSETTTAIHTLTS 415
            ||   .:|.:    ..||.::      |...::.||..:..|....:|:            .|..
Mosquito   389 LAAGSNNGTVIAPSEEKPQYDAGAGEGGGDESDEGGGTASPPSLAGELR------------PLQR 441

  Fly   416 NSNGHVHKPTQIVTPTRRASDSDKENTYTATFVKKPVATIQLGSSNGIEDATVVATLTLFPDAPT 480
            |:||   ....:|.|:..:|.|.::|       |:.|..:. |...|:..::  |...|||||||
Mosquito   442 NNNG---GGGTMVIPSDASSASTEDN-------KENVIVVG-GGGGGLVVSS--AACALFPDAPT 493

  Fly   481 TPKVIRKTPTGESNGSATSVKALVKKFQLEDSSGSAVARRSGGAVTSSSGLHSPTTTSVRLNSIR 545
            ||||.||         |..|:.|                ..||      |||
Mosquito   494 TPKVSRK---------ALPVEPL----------------NDGG------GLH------------- 514

  Fly   546 RASEPLTTVYKKQTSQNGCSSTSNPSSSPGSSPTTSGSTATLLIHSQRLGNSTAPASHCVAVPAT 610
                     |..|
Mosquito   515 ---------YNLQ---------------------------------------------------- 518

  Fly   611 ATATSSASSSNSSSGKSTSAAHHLHHHHMHHHHHHHHHH 649
                                .||.||||:.||:||||||
Mosquito   519 --------------------QHHHHHHHLQHHNHHHHHH 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Drak	NP_996411.2	STKc_DRAK	28..295	CDD:271008	167/267 (63%)
		PHA03255	379..>554	CDD:165513	39/174 (22%)
Drak	XP_311247.6	None