DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spase25 and SPCS2

DIOPT Version :10

Sequence 1:NP_572723.1 Gene:Spase25 / 32095 FlyBaseID:FBgn0030306 Length:199 Species:Drosophila melanogaster
Sequence 2:NP_055567.2 Gene:SPCS2 / 9789 HGNCID:28962 Length:226 Species:Homo sapiens


Alignment Length:192 Identity:78/192 - (40%)
Similarity:127/192 - (66%) Gaps:10/192 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 KKDEKSQQGEELVKVNKWDGSAVKHALDDAVKTCLLGDRPQLKEQFGLVNTRLALCALAVSVAIM 67
            |.|:|.      ||::||||||||::|||:.|..|| ::.:..|.|||::.||.:|.::...||:
Human    40 KIDDKP------VKIDKWDGSAVKNSLDDSAKKVLL-EKYKYVENFGLIDGRLTICTISCFFAIV 97

  Fly    68 AHAWDFTHPFPESRPVLLFSVLAYFALLGILTLHSSFREKGTFAVALQKD---KERERLWEASSD 129
            |..||:.||||||:|||...|::||.::||||:::|::||..|.||.:||   .:.:.:|:.||.
Human    98 ALIWDYMHPFPESKPVLALCVISYFVMMGILTIYTSYKEKSIFLVAHRKDPTGMDPDDIWQLSSS 162

  Fly   130 MRKYDDKYLLTLSVRDTKNGKRREQSSNKSCAAFIDQNGIVLDNLVANEVNRLFNALAADKK 191
            ::::||||.|.|:....:..::||....||.|.|.|.:|.::.:....|::||.::||.::|
Human   163 LKRFDDKYTLKLTFISGRTKQQREAEFTKSIAKFFDHSGTLVMDAYEPEISRLHDSLAIERK 224

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spase25NP_572723.1 SPC25 30..184 CDD:461993 61/156 (39%)
SPCS2NP_055567.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..25
SPC25 61..217 CDD:461993 61/156 (39%)
Blue background indicates that the domain is not in the aligned region.

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