Protein Alignment Uba5 and UBA1

DIOPT Version :10

• Sequence 1: NP_572722.2
• Gene: Uba5 / 32094
• FlyBaseID: FBgn0030305
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_012712.1
• Gene: UBA1 / 853670
• SGDID: S000001693
• Length: 1024
• Species: Saccharomyces cerevisiae
• Alignment Length: 484
• Identity: 114/484 - (23%)
• Similarity: 182/484 - (37%)
• Gaps: 144/484 - (29%)

  Fly     6 DELQAIIADLKTELETEPKSSG-GVASNSRL-------ARDRIDRMSA--------EVVDS---- 50
            :||..::.||..:   :|:..| ||..|..|       ||..|..:.|        ||:.:
Yeast   320 NELIKLVTDLSVQ---QPEVLGEGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGK 381

  Fly    51 -NPYSRLM---ALQRMNIVKDYER---------IRY-KAVAIVGVG-------------GVGSVT 88
             .|..:.|   :|:.:...|::.|         .|| ..:|:.|:.             |.|::.
Yeast   382 FTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIG 446

  Fly    89 ADMLTRCGI--------GKLILFDYDKVELANMNRLF-FTPDQAGLSKVAAAAATLSFINPDVEI 144
            .:||....:        |.:::.|.|.:|.:|:||.| |.|...|.:|...||..:..:|||::.
Yeast   447 CEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKG 511

  Fly   145 ETHNYNITTV--ENFDRFLDTISQGGRIAGQPVDLVLSCVDNFEARMAINAACNERNLNWFESGV 207
            :. |..|..|  |..:.|.|:.       .:.:|.|.:.:||.:||..::..|........|||.
Yeast   512 KI-NAKIDKVGPETEEIFNDSF-------WESLDFVTNALDNVDARTYVDRRCVFYRKPLLESGT 568

  Fly   208 SENAVSGHIQFIRPGDTACFACA--PPLVVAENIDEKTLKREGVCA-ASLPTTMGITAGFL---- 265
            .  ...|:.|.|.|..|..::.:  ||        ||::.   :|. .|.|..:..|..:.
Yeast   569 L--GTKGNTQVIIPRLTESYSSSRDPP--------EKSIP---LCTLRSFPNKIDHTIAWAKSLF 620

  Fly   266 -------VQNALKYLL--NF--------GEVSDYLGYNALSDFFPKMTLKPN--PQCDDRNCLVR 311
                   .:|...||.  ||        |:|...|  .::||   .::.||:  ..|.....|..
Yeast   621 QGYFTDSAENVNMYLTQPNFVEQTLKQSGDVKGVL--ESISD---SLSSKPHNFEDCIKWARLEF 680

  Fly   312 QKEFQARPKPVLI----EEKAVSEEPLHATNEWGIELVAEDAPESNTTPAETP----------VM 362
            :|:|....|.:|.    :.|..:.||.     |.   .|:.||    ||.|..          |.
Yeast   681 EKKFNHDIKQLLFNFPKDAKTSNGEPF-----WS---GAKRAP----TPLEFDIYNNDHFHFVVA 733

  Fly   363 GEGLRLAYEAPEKSSETSEETVSAATADE 391
            |..|| ||....||.:::    |....||
Yeast   734 GASLR-AYNYGIKSDDSN----SKPNVDE 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	69/305 (23%)
UBA1	NP_012712.1	Ube1	13..1023	CDD:273603	114/484 (24%)