Protein Alignment Uba5 and Atg7

DIOPT Version :10

• Sequence 1: NP_572722.2
• Gene: Uba5 / 32094
• FlyBaseID: FBgn0030305
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_001240646.1
• Gene: Atg7 / 74244
• MGIID: 1921494
• Length: 741
• Species: Mus musculus
• Alignment Length: 355
• Identity: 78/355 - (21%)
• Similarity: 124/355 - (34%)
• Gaps: 68/355 - (19%)

  Fly     1 MSHAIDELQAIIADLK-TELETEP----------KSSGGVASNSRLARDRID--RMSAEVVDSNP 52
            |..|.|...:||.::| .|:...|          ...||:..........:|  |::...||.|
Mouse   312 MQGARDVTHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSGCMDPKRLAESSVDLN- 375

  Fly    53 YSRLMALQRMNIVKDYERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNR-- 115
             .:||. .|:....|.:::......::|.|.:|...|..|...|:..:...|..|:..:|..|
Mouse   376 -LKLMC-WRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHVTFVDNAKISYSNPVRQP 438

  Fly   116 LFFTPD--QAGLSKVAAAAATLSFINPDVEIETHNYNITTVENFDRFLD-TISQGGRIAGQ---- 173
            |:...|  ..|..|..|||..|..|.|.|.....|.:|....:...|.| |:.|..|...|
Mouse   439 LYEFEDCLGGGKPKALAAAERLQKIFPGVNARGFNMSIPMPGHPVNFSDVTMEQARRDVEQLEQL 503

  Fly   174 --PVDLVLSCVDNFEAR------------MAINAACNERNLNWFESGVSENAVSG-------HIQ 217
              ..|::...:|..|:|            :.||||...........|:.:....|       |:
Mouse   504 IDNHDVIFLLMDTRESRWLPTVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCPSHL- 567

  Fly   218 FIRPGD-------------TACFACAPPLVVAENIDEKTLKREGVCAASLPTTMGITAGFLVQNA 269
             :.|.|             ..|:.|...:...::..::||.::  |..|.| .:.:.||.|....
Mouse   568 -VAPADLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQ--CTVSRP-GLAVIAGALAVEL 628

  Fly   270 LKYLLNFGEVSDYLGYNALSDFFPKMTLKP 299
            :..:|...|.    ||...|....:|...|
Mouse   629 MVSVLQHPEG----GYAIASSSDDRMNEPP 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	62/287 (22%)
Atg7	NP_001240646.1	E1_like_apg7	54..740	CDD:273590	78/355 (22%)