Protein Alignment Uba5 and UBA7

DIOPT Version :10

• Sequence 1: NP_572722.2
• Gene: Uba5 / 32094
• FlyBaseID: FBgn0030305
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_003326.2
• Gene: UBA7 / 7318
• HGNCID: 12471
• Length: 1012
• Species: Homo sapiens
• Alignment Length: 384
• Identity: 79/384 - (20%)
• Similarity: 132/384 - (34%)
• Gaps: 92/384 - (23%)

  Fly    69 ERIRYKAVAIVGVGGVGSVTADMLTRCGIGK-----LILFDYDKVELANMNRLF-FTPDQAGLSK 127
            |::|.:...:||.|.:|.....:....|:|.     |.:.|.|.:|.:|::|.| |.....|..|
Human   428 EKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPK 492

  Fly   128 VAAAAATLSFINPDVEIETHNYNI-TTVENF--DRFLDTISQGGRIAGQPVDLVLSCVDNFEARM 189
            ...|||....:|||:::....|.: .|.|:.  |.|...           ||.|.:.:|:|:||.
Human   493 AEVAAAAARGLNPDLQVIPLTYPLDPTTEHIYGDNFFSR-----------VDGVAAALDSFQARR 546

  Fly   190 AINAACNERNLNWFESGVSENAVSG-----HI--QFIRPGDTACFACAP-PL------------- 233
            .:.|.|........|:|.|....|.     |:  .:..|...|....|| |:
Human   547 YVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHT 611

  Fly   234 -------------VVAENIDEKTLKREGVCAASLPTTMGITAGFL---------VQNALKYLLNF 276
                         :.||.|:........:.....|.|:.:....|         .|:.:.:.|..
Human   612 LQWARHEFEELFRLSAETINHHQQAHTSLADMDEPQTLTLLKPVLGVLRVRPQNWQDCVAWALGH 676

  Fly   277 GEVSDYLGYNALSDFFPKMTLKPNPQCDD--------RNCLVRQKEFQARPKPVLIEEKAVSE-- 331
            .::..:.|...|...||     ||...:|        :.| .:..||.......|:...|.:.
Human   677 WKLCFHYGIKQLLRHFP-----PNKVLEDGTPFWSGPKQC-PQPLEFDTNQDTHLLYVLAAANLY 735

  Fly   332 ---EPLHATNEWG-----IELVAEDAPESNTTPAETPVMGEGLRLAYEAPEKSSETSEE 382
               ..|..:.:|.     ::|:.:..|:.     ..|:....|.||..:.|...|..:|
Human   736 AQMHGLPGSQDWTALRELLKLLPQPDPQQ-----MAPIFASNLELASASAEFGPEQQKE 789

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	60/279 (22%)
UBA7	NP_003326.2	Ube1	10..1010	CDD:273603	79/384 (21%)
		2 approximate repeats	23..575		42/157 (27%)