DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Uba5 and nae1

DIOPT Version :9

Sequence 1:	NP_572722.2	Gene:	Uba5 / 32094	FlyBaseID:	FBgn0030305	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_956793.1	Gene:	nae1 / 573336	ZFINID:	ZDB-GENE-040426-1552	Length:	533	Species:	Danio rerio

Alignment Length:	145	Identity:	33/145 - (22%)
Similarity:	53/145 - (36%)	Gaps:	36/145 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 TEPKSSGGVASNSRLARDRIDRMSAEVVDSNPYSRLMALQRMNIVKDY--ERIRYKAVAIVGVGG 83
            |:||:|         ...|.||                  ::.:..|:  |.:....|.::....
Zfish     2 TDPKTS---------KEQRYDR------------------QLRLWGDHGQEALENAHVCLINATA 39

  Fly    84 VGSVTADMLTRCGIGKLILFDYDKVELANMNRLFFTPDQA-GLSKVAAAAATLSFINPDVEIETH 147
            .|:.....|...|||...:.|..||...::...||....| |.::..||...|..:|.||   :.
Zfish    40 SGTEILKNLVLPGIGAFTIVDGHKVSGEDVGNNFFLSSSAIGKNRAQAATELLQELNSDV---SG 101

  Fly   148 NYNITTVENFDRFLD 162
            |:   ..|:.|:.||
Zfish   102 NF---VEESPDKLLD 113

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	26/114 (23%)
Uba5	NP_572722.2	ThiF	53..310	CDD:279270	26/113 (23%)
nae1	NP_956793.1	ThiF	6..>164	CDD:223552	30/141 (21%)
		APPBP1_RUB	10..531	CDD:238770	29/128 (23%)
		Interaction with uba3. /evidence=ECO:0000250	330..343
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900