Protein Alignment Uba5 and Sae1

DIOPT Version :10

• Sequence 1: NP_572722.2
• Gene: Uba5 / 32094
• FlyBaseID: FBgn0030305
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_062722.1
• Gene: Sae1 / 56459
• MGIID: 1929264
• Length: 350
• Species: Mus musculus
• Alignment Length: 367
• Identity: 73/367 - (19%)
• Similarity: 125/367 - (34%)
• Gaps: 89/367 - (24%)

  Fly    19 LETEPKSSGGVASNSRLARDRIDRMSAEVVDSNPYSRLMALQRMNIVKDYERIRYKAVAIVGVGG 83
            :|.|....||....|.....:.||.          .||..|:..      :|:|...|.|||:.|
Mouse     2 VEKEEAGGGGGGGISEEEAAQYDRQ----------IRLWGLEAQ------KRLRASRVLIVGMKG 50

  Fly    84 VGSVTADMLTRCGIGKLILFDYDKVELANMNRLF-FTPDQAGLSKVAAAAATLSFINP--DVEIE 145
            :|:..|..|...|:..|.:.|:::|...:....| ......|.::..|:......:||  ||:::
Mouse    51 LGAEIAKNLILAGVKGLTMLDHEQVSPEDPGAQFLIQTGSVGRNRAEASLERAQNLNPMVDVKVD 115

  Fly   146 THNYNITTVENFDRFLDTISQGGRIAGQPVDLVLSCVDNFEARMAINAACNERNLNWFESGV--- 207
            |.:........|.:| |.:             .|:|... :..:.::..|:..::.:|...|
Mouse   116 TEDVEKKPESFFTKF-DAV-------------CLTCCSR-DVIIKVDQICHRNSIKFFTGDVFGY 165

  Fly   208 ---------------SENAVSGHIQFIRPGDTACFA----------------CAPPLVVAENIDE 241
                           .:..|:...|.:..|..|..|                |  |:..|..:|.
Mouse   166 HGYTFANLGEHEFVEEKTKVAKVSQGVEDGPEAKRAKLDSSETTMVKKKVLFC--PVKEALEVDW 228

  Fly   242 KTLKREGVCAASLPTTMGITAGFLVQNALKYLLNFGEVSDYLGY--------NALSDFFPKMTLK 298
            ...|.:.....:.|..      ||:|..||:..:.|.......|        ...:|.|..:.:.
Mouse   229 SGEKAKAALKRTAPDY------FLLQVLLKFRTDKGRDPTSESYKEDAELLLQIRNDVFDSLGIS 287

  Fly   299 PNPQCDD--RNCLVRQKEFQARPKPVLIEE--KAVSE-EPLH 335
            |:...||  |.|........|....:|.:|  ||:|: :|.|
Mouse   288 PDLLPDDFVRYCFSEMAPVCAVVGGILAQEIVKALSQRDPPH 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	53/289 (18%)
Sae1	NP_062722.1	Aos1_SUMO	20..345	CDD:238769	68/349 (19%)