DRSC/TRiP Functional Genomics Resources

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Protein Alignment Uba5 and Uba3

DIOPT Version :9

Sequence 1:NP_572722.2 Gene:Uba5 / 32094 FlyBaseID:FBgn0030305 Length:404 Species:Drosophila melanogaster
Sequence 2:NP_610913.1 Gene:Uba3 / 36539 FlyBaseID:FBgn0263697 Length:450 Species:Drosophila melanogaster


Alignment Length:402 Identity:95/402 - (23%)
Similarity:137/402 - (34%) Gaps:112/402 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    76 VAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLF-FTPDQAGLSKVAAAAATLSFIN 139
            |.|:|.||:|......|...|.|.|.:.|.|.:||:|:||.| |.....|.||...||   .|||
  Fly    51 VLIIGAGGLGCELLKDLALMGFGNLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAA---RFIN 112

  Fly   140 ---PDVEIETHNYNITTVENFDRFLDTISQGGRIAGQPVDLVLSCVDNFEARMAINAACNERNLN 201
               |...:..|   ...:::||...          .|...||:..:|:..||..||...... |.
  Fly   113 ARVPTCRVTPH---FKKIQDFDESF----------YQQFHLVVCGLDSIVARRWINGMLLSM-LR 163

  Fly   202 WFESGVSENA------------VSGHIQFIRPGDTACFACA----PPLV------VAEN------ 238
            :.|.|..:.:            ..|:.:.|.||.|||..|.    ||.|      :|..      
  Fly   164 YEEDGTIDTSSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVNYPLCTIANTPRLPEH 228

  Fly   239 ------------------------------IDEKTLKR--------------EGVCAASLPTTMG 259
                                          |.|:.|:|              :||....:|....
  Fly   229 CIEYVKIIQWEKQNPFGVPLDGDDPQHIGWIYERALERSNEFNITGVTYRLVQGVVKHIIPAVAS 293

  Fly   260 ITAGFLVQNALKYL----LNFGEVSDYLGYNALSDFFPKMTLKPNPQCDDRNCLVRQKEFQARPK 320
            ..|......||:..    ..:..:::||.:|.|...: ..|.:..   ...|||....    .|:
  Fly   294 TNAAIAAACALEVFKLATSCYDSMANYLNFNDLDGIY-TYTYEAE---KSENCLACSN----TPQ 350

  Fly   321 PVLIEEKAVSEEPLHATNEWGIELVAEDAPESNTTPAETPVMGEG-LRLAYEAPEKSSETSEETV 384
            |:.|      |:|...|.|..|:|:.:.......:||.|.||.:| .|..|.:..||.|.:....
  Fly   351 PLPI------EDPNTTTLEDVIKLLCDSPRFQLKSPALTTVMKDGKRRTLYMSGVKSIEEATRKN 409

  Fly   385 SAATADETSLED 396
            ...:..|..|.|
  Fly   410 LTQSLGELGLHD 421

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Uba5NP_572722.2 ThiF_MoeB_HesA_family 52..297 CDD:238386 68/300 (23%)
ThiF 53..310 CDD:279270 71/313 (23%)
Uba3NP_610913.1 ThiF 48..>220 CDD:279270 53/185 (29%)
Uba3_RUB 50..346 CDD:238765 72/315 (23%)
E2_bind 357..442 CDD:285976 19/65 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45446839
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0476
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR10953
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
43.840

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