DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Uba5 and Uba5

DIOPT Version :9

Sequence 1:	NP_572722.2	Gene:	Uba5 / 32094	FlyBaseID:	FBgn0030305	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001009669.1	Gene:	Uba5 / 300968	RGDID:	1311702	Length:	403	Species:	Rattus norvegicus

Alignment Length:	409	Identity:	259/409 - (63%)
Similarity:	306/409 - (74%)	Gaps:	11/409 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSHAIDELQAIIADLKTELETEPKSSGGVASNSRLARDRIDRMSAEVVDSNPYSRLMALQRMNIV 65
            |:.:::.|...:.:|:.||..|  .|..:|.:....|.||.:||.||||||||||||||:||.:|
  Rat     1 MAESVERLLQRVEELEQELARE--RSRRIAGDGHCGRTRIQKMSDEVVDSNPYSRLMALKRMGVV 63

  Fly    66 KDYERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLFFTPDQAGLSKVAA 130
            .|||:||..|||||||||||||||:||||||||||:|||||||||||||||||.|.|||:|||.|
  Rat    64 SDYEKIRTYAVAIVGVGGVGSVTAEMLTRCGIGKLLLFDYDKVELANMNRLFFQPYQAGMSKVQA 128

  Fly   131 AAATLSFINPDVEIETHNYNITTVENFDRFLDTISQGGRIAGQPVDLVLSCVDNFEARMAINAAC 195
            |..||..|||||..|.|||||||||:|:.|::.||.||...|||||||||||||||||||||.||
  Rat   129 AEHTLRSINPDVLFEVHNYNITTVEHFEHFMNRISNGGLEEGQPVDLVLSCVDNFEARMAINTAC 193

  Fly   196 NERNLNWFESGVSENAVSGHIQFIRPGDTACFACAPPLVVAENIDEKTLKREGVCAASLPTTMGI 260
            ||....|.||||||||||||||.:.||::||||||||||||.||||||||||||||||||||||:
  Rat   194 NELGQTWMESGVSENAVSGHIQLMVPGESACFACAPPLVVASNIDEKTLKREGVCAASLPTTMGV 258

  Fly   261 TAGFLVQNALKYLLNFGEVSDYLGYNALSDFFPKMTLKPNPQCDDRNCLVRQKEFQARPKPVLIE 325
            .||.||||.||:||.||.||.||||||:.||||.|.:||||||||:||..:|:|::.|......:
  Rat   259 VAGILVQNVLKFLLKFGTVSFYLGYNAMQDFFPTMFMKPNPQCDDKNCRKQQEEYKKRAPAQPTQ 323

  Fly   326 EKAVSEEP--LHATNEWGIELVAEDAPES-NTTPAETPVMGEGLRLAYEAPEKSSETSEETVSAA 387
            |.|..||.  :|..||||||||:|.:.|. ..:....|.:.||:.:||..|:|    .|::||..
  Rat   324 ETAPQEEEEVVHEDNEWGIELVSEVSEEELKNSSGPVPTLPEGITVAYTVPKK----REDSVSEV 384

  Fly   388 TADET--SLEDLMAQMKSM 404
            |.:::  |||||||:||.|
  Rat   385 TVEDSGESLEDLMARMKKM 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	191/244 (78%)
Uba5	NP_572722.2	ThiF	53..310	CDD:279270	200/256 (78%)
Uba5	NP_001009669.1	ThiF_MoeB_HesA_family	50..293	CDD:238386	190/242 (79%)
		ThiF	51..307	CDD:279270	200/255 (78%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..337		10/32 (31%)
		UFM1-interacting sequence (UIS). /evidence=ECO:0000250\|UniProtKB:Q9GZZ9	333..345		7/13 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166353920
Domainoid	1	1.000	408	1.000	Domainoid score	I677
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11738
Inparanoid	1	1.050	495	1.000	Inparanoid score	I1338
OMA	1	1.010	-	-		QHG54107
OrthoDB	1	1.010	-	-		D1092362at2759
OrthoFinder	1	1.000	-	-		FOG0006244
OrthoInspector	1	1.000	-	-		oto96750
orthoMCL	1	0.900	-	-		OOG6_104369
Panther	1	1.100	-	-	LDO	PTHR10953
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4526
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770