Protein Alignment Uba5 and Nae1

DIOPT Version :10

• Sequence 1: NP_572722.2
• Gene: Uba5 / 32094
• FlyBaseID: FBgn0030305
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_659180.1
• Gene: Nae1 / 234664
• MGIID: 2384561
• Length: 534
• Species: Mus musculus
• Alignment Length: 223
• Identity: 45/223 - (20%)
• Similarity: 75/223 - (33%)
• Gaps: 64/223 - (28%)

  Fly     6 DELQAIIADLKTELETE--PKSSGGVASNSR-------------LARDRIDRMSAE--------- 46
            :..:..|.::.|.|.|.  |.|...:.::.|             |||...:.::.|
Mouse   263 ENFEEAIKNVNTALNTTQIPSSIEDIFNDDRCINITKQTPTFWILARALKEFVAKEGQGNLPVRG 327

  Fly    47 -----VVDSNPYSRLMALQRMNIVKDYERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYD 106
                 :.|||.|.:|..:.|....||             ...||:..|.:|...|.....:.: .
Mouse   328 TIPDMIADSNKYIKLQNVYREKAKKD-------------AAAVGNHVAKLLQSVGQAPESISE-K 378

  Fly   107 KVELANMNRLFF-------TPDQAGLSKVAAAAATLSFINPDVEIETHNYNITTVENFDRFLDTI 164
            :::|...|..|.       ..::.||..|.......|..|||.||..: ..:..|:.|.:
Mouse   379 ELKLLCSNSAFLRVVRCRSLAEEYGLDTVNKDEIISSMDNPDNEIVLY-LMLRAVDRFHK----- 437

  Fly   165 SQGGRIAG-------QPVDLVLSCVDNF 185
             |.||..|       :.:..:.||:..|
Mouse   438 -QHGRYPGVSNYQVEEDIGKLKSCLTGF 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	31/148 (21%)
Nae1	NP_659180.1	APPBP1_RUB	11..532	CDD:238770	45/223 (20%)
		Interaction with UBA3. /evidence=ECO:0000250	331..344		5/12 (42%)