DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba5 and moc-3

DIOPT Version :9

Sequence 1:	NP_572722.2	Gene:	Uba5 / 32094	FlyBaseID:	FBgn0030305	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_501359.1	Gene:	moc-3 / 177607	WormBaseID:	WBGene00018357	Length:	402	Species:	Caenorhabditis elegans

Alignment Length:	191	Identity:	54/191 - (28%)
Similarity:	84/191 - (43%)	Gaps:	24/191 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 DSNPYSRLMALQRMNIVKDYERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANM 113
            |:..|||.:.:.... |...:.::...|.|||.||:|...|..|...|||.:.:.|||.:.|.|:
Worm    14 DAGRYSRQLLVDDFG-VSGQKNLKNLNVLIVGAGGLGCPVATYLGAAGIGTIGIVDYDHISLDNL 77

  Fly   114 NR-LFFTPDQAGLSKVAAAAATLSFINPDVEIETHNYNITTVENFDRFLDTISQGGRIAGQPVDL 177
            :| :.:..||.|.||..|.|..:...|.|:.::.||.::.:......|            :..::
Worm    78 HRQVAYKEDQVGKSKAQALADNIKLQNSDLNVQVHNTSLDSSNAMQLF------------KNYEI 130

  Fly   178 VLSCVDNFEARMAINAACNERNLNWFESGVSENAV--SGHIQFIRPG-DTACFAC---APP 232
            |..|.||...|..||..|...|:..    ||.:|:  .|.:.....| |..|:.|   :||
Worm   131 VCDCTDNVATRYLINDVCVLLNIPL----VSGSALRWDGQLSVYHYGSDCPCYRCLFPSPP 187

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	53/188 (28%)
Uba5	NP_572722.2	ThiF	53..310	CDD:279270	53/187 (28%)
moc-3	NP_501359.1	PRK07878	8..402	CDD:181156	54/191 (28%)
		ThiF_MoeB_HesA_family	17..246	CDD:238386	53/188 (28%)
		RHOD_ThiF	283..402	CDD:238784
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0476
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810