Protein Alignment Uba5 and ATG7

DIOPT Version :10

• Sequence 1: NP_572722.2
• Gene: Uba5 / 32094
• FlyBaseID: FBgn0030305
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: XP_054200913.1
• Gene: ATG7 / 10533
• HGNCID: 16935
• Length: 768
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 78/358 - (21%)
• Similarity: 125/358 - (34%)
• Gaps: 73/358 - (20%)

  Fly     1 MSHAIDELQAIIADLK-TELETEP----------KSSGGVASNSRLARDRID--RMSAEVVDSNP 52
            |..|.|...:||.::| .|:...|          ...||:........:.:|  |::...||.|
Human   273 MQGARDVAHSIIFEVKLPEMAFSPDCPKAVGWEKNQKGGMGPRMVNLSECMDPKRLAESSVDLN- 336

  Fly    53 YSRLMALQRMNIVKDYERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNR-- 115
             .:||. .|:....|.:::......::|.|.:|...|..|...|:..:...|..|:..:|..|
Human   337 -LKLMC-WRLVPTLDLDKVVSVKCLLLGAGTLGCNVARTLMGWGVRHITFVDNAKISYSNPVRQP 399

  Fly   116 LFFTPD--QAGLSKVAAAAATLSFINPDVEIETHNYNI-----------TTVENFDRFLDTISQG 167
            |:...|  ..|..|..|||..|..|.|.|.....|.:|           .|:|...|.::.:.|
Human   400 LYEFEDCLGGGKPKALAAADRLQKIFPGVNARGFNMSIPMPGHPVNFSSVTLEQARRDVEQLEQ- 463

  Fly   168 GRIAGQPVDLVLSCVDNFEAR------------MAINAACNERNLNWFESG-------------- 206
               ..:..|:|...:|..|:|            :.||||...........|
Human   464 ---LIESHDVVFLLMDTRESRWLPAVIAASKRKLVINAALGFDTFVVMRHGLKKPKQQGAGDLCP 525

  Fly   207 ---VSENAVSGHIQFIR-PG-DTACFACAPPLVVAENIDEKTLKREGVCAASLPTTMGITAGFLV 266
               |:...:.|...|.. || ...|:.|...:...::..::||.::  |..|.| .:.:.||.|.
Human   526 NHPVASADLLGSSLFANIPGYKLGCYFCNDVVAPGDSTRDRTLDQQ--CTVSRP-GLAVIAGALA 587

  Fly   267 QNALKYLLNFGEVSDYLGYNALSDFFPKMTLKP 299
            ...:..:|...|.    ||...|....:|...|
Human   588 VELMVSVLQHPEG----GYAIASSSDDRMNEPP 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	62/290 (21%)
ATG7	XP_054200913.1	E1_like_apg7	15..695	CDD:273590	78/358 (22%)