Protein Alignment Uba5 and UBA2

DIOPT Version :10

• Sequence 1: NP_572722.2
• Gene: Uba5 / 32094
• FlyBaseID: FBgn0030305
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_005490.1
• Gene: UBA2 / 10054
• HGNCID: 30661
• Length: 640
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 65/249 - (26%)
• Similarity: 94/249 - (37%)
• Gaps: 77/249 - (30%)

  Fly    57 MALQRMNIVKDYERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNRLF-FTP 120
            |||.|....:..|.:....|.:||.||:|......|...|...:.|.|.|.::::|:||.| |..
Human     1 MALSRGLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLDTIDVSNLNRQFLFQK 65

  Fly   121 DQAGLSKVAAAAATL--------------SFINPDVEIETHNYNITTVENFDRFLDTISQGGRIA 171
            ...|.||...|..::              |.:|||       ||   ||.|.:|:
Human    66 KHVGRSKAQVAKESVLQFYPKANIVAYHDSIMNPD-------YN---VEFFRQFI---------- 110

  Fly   172 GQPVDLVLSCVDNFEARMAINAACNERNLNWFESGVSENAVSGHIQFIRPGDTACFACAPPLVVA 236
                 ||::.:||..||..:|..|...::...|||.:  ...|.:..|:.|.|.|:.|.|
Human   111 -----LVMNALDNRAARNHVNRMCLAADVPLIESGTA--GYLGQVTTIKKGVTECYECHP----- 163

  Fly   237 ENIDEKTLKREGVCAASLPTTMGITAGFLVQNA----------LKYLLN--FGE 278
                 |..:|      :.|       |..::|.          .|||.|  |||
Human   164 -----KPTQR------TFP-------GCTIRNTPSEPIHCIVWAKYLFNQLFGE 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	65/249 (26%)
UBA2	NP_005490.1	Uba2_SUMO	19..444	CDD:238766	60/231 (26%)
		UBA_E1_SCCH	179..362	CDD:463157	7/21 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	202..231
		UAE_UbL	452..538	CDD:464286
		UBA2_C	549..635	CDD:465058
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	551..640