DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba5 and mocs3

DIOPT Version :9

Sequence 1:	NP_572722.2	Gene:	Uba5 / 32094	FlyBaseID:	FBgn0030305	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_031758108.1	Gene:	mocs3 / 100491723	XenbaseID:	XB-GENE-5804173	Length:	455	Species:	Xenopus tropicalis

Alignment Length:	332	Identity:	78/332 - (23%)
Similarity:	117/332 - (35%)	Gaps:	96/332 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 SHAIDELQAIIADLKTELETEPKSSGGVASNSRLARDRIDRMSAEVVDSNPYSRLMALQRMNIVK 66
            ||..||   |:.:|.....|.|                         |...|||.:.|.... |:
Frog    37 SHGADE---ILPELNKSSLTNP-------------------------DILRYSRQLVLPEFG-VQ 72

  Fly    67 DYERIRYKAVAIVGVGGVGSVTADMLTRCGIGKLILFDYDKVELANMNR-LFFTPDQAGLSKVAA 130
            ....:...:|.::|.||:|...|..|...|||:|.|.|||.||::|::| :....::.|:.|..:
Frog    73 GQLNLSKVSVLVIGCGGLGCPVAQYLAASGIGRLGLLDYDVVEMSNLHRQVLHGENRLGMPKSVS 137

  Fly   131 AAATLSFINPDVEIETHNYNITTVENFDRFLDTISQGGRIAGQPVDLVLSCVDNFEARMAINAAC 195
            ...||..:|..|....::.::    |.:..|..|.|        .|::..|.||...|..:|.||
Frog   138 IVKTLQKLNSSVIYLPYHMSL----NPENGLQIIRQ--------YDIIADCSDNVPTRYLVNDAC 190

  Fly   196 --------NERNLNWFESGVSENAVSGHIQFIRPGDTACFAC----APPLVVAENIDEKTLKREG 248
                    :...|.|          .|.:.........|:.|    .||.....|
Frog   191 VLAGKPLVSASALRW----------EGQLTVYNYQQGPCYRCLFPKPPPSETVTN---------- 235

  Fly   249 VCAASLPTTMGITAGFLVQ-NALKYL-LNFGEVSDYLG----YNALSDFFPKMTLKPNPQCDDRN 307
             ||..  ..:||..|.:.. .||:.| :..|.|..|.|    ::||...|             ||
Frog   236 -CADG--GVLGIVPGIIGSLQALEVLKIASGMVPSYSGVLLMFDALEGRF-------------RN 284

  Fly   308 CLVRQKE 314
            ..:|.|:
Frog   285 IKIRGKQ 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	65/263 (25%)
Uba5	NP_572722.2	ThiF	53..310	CDD:279270	67/275 (24%)
mocs3	XP_031758108.1	ThiF_MoeB_HesA_family	59..287	CDD:238386	67/276 (24%)
mocs3	XP_031758108.1	RHOD	324..455	CDD:412175
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910