DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Uba5 and uba7

DIOPT Version :9

Sequence 1:	NP_572722.2	Gene:	Uba5 / 32094	FlyBaseID:	FBgn0030305	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_005155933.1	Gene:	uba7 / 100001302	ZFINID:	ZDB-GENE-121120-4	Length:	1016	Species:	Danio rerio

Alignment Length:	324	Identity:	72/324 - (22%)
Similarity:	115/324 - (35%)	Gaps:	98/324 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LETEPKSSGGVASNSRLA-RD-RIDRMSAEVVDSNPYSRLMALQRMNIVKDYE-RIRYKAVAIVG 80
            ||..|:..|||.|....| || |.|...| |..|                |:: :::.:...:||
Zfish   386 LECLPQEEGGVLSEDACAPRDSRYDGQIA-VFGS----------------DFQNKLKKQKYFLVG 433

  Fly    81 VGGVGSVTADMLTRCGI-----GKLILFDYDKVELANMNRLF-FTPDQAGLSKVAAAAATLSFIN 139
            .|.:|..........|:     |.:.:.|.|.:|.:|:||.| |.....|..|..|||..:..:|
Zfish   434 AGAIGCELLKNFALIGLGAGEGGSITVTDMDSIERSNLNRQFLFRSQDIGRPKSEAAAEAVKEMN 498

  Fly   140 PDVEIETHNYNITTVENFDRFLDTISQGGRIAGQP-----------VDLVLSCVDNFEARMAINA 193
            |                   |::.|:|..|:..:.           :|.|.:.:||.:||:.::.
Zfish   499 P-------------------FMNIIAQQNRVCAETEEVYTHSFYTGLDGVAAALDNVDARVYLDQ 544

  Fly   194 ACNERNLNWFESGVSENAVSGHIQFIRPGDTACFAC-------APPLVVAENID---EKTLK--- 245
            .|........|.|...:  .||...:.|..|..:..       |.|:...:|..   |.||:
Zfish   545 CCVRNKKPMLEGGTLGS--KGHTMVVVPRLTESYGLSSSGGQKAIPICTLKNFPHRIEHTLQWAR 607

  Fly   246 --REGVCAASLPTTMGITAGFLVQNALKYLLNFGEVSDYLG-------------YNALSDFFPK 294
              .||:...:            .||...:|.:.|.|...:.             |.:|||.:|:
Zfish   608 DHFEGLFKQT------------AQNVNNFLSDPGFVDRTVARGDVEAVEMLEGVYRSLSDDWPE 659

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Uba5	NP_572722.2	ThiF_MoeB_HesA_family	52..297	CDD:238386	57/289 (20%)
Uba5	NP_572722.2	ThiF	53..310	CDD:279270	57/288 (20%)
uba7	XP_005155933.1	Ube1	5..1013	CDD:273603	72/324 (22%)
		Ube1_repeat1	10..393	CDD:238768	3/6 (50%)
		E1_4HB	258..326	CDD:292809
		E1_enzyme_family	428..970	CDD:304554	56/265 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910