DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4g15 and CYP86C4

DIOPT Version :9

Sequence 1:	NP_572721.1	Gene:	Cyp4g15 / 32093	FlyBaseID:	FBgn0030304	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_172774.1	Gene:	CYP86C4 / 837873	AraportID:	AT1G13150	Length:	529	Species:	Arabidopsis thaliana

Alignment Length:	577	Identity:	124/577 - (21%)
Similarity:	233/577 - (40%)	Gaps:	147/577 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 GPRGLPIVG-------HLFDVIGPASSVFRTVIRKSAPFEHIAKMWIGPKLVVFIYDPRDVELLL 105
            ||...|:.|       |:.||.|   .|.|::.:....|.: ..:|:..........|.:||.:|
plant    38 GPMLWPVFGITLEFFFHINDVYG---WVTRSLKKCRGTFLY-RGVWLDGSYGAVTCVPANVEYML 98

  Fly   106 SSHV-YIDKASEYKF-FKPWLGDGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVVR 168
            .::. ...|.:.:|. |...|.:|:..:....|:..|::|....|..   .|:|...:.::::||
plant    99 KTNFKNFPKGTFFKSRFNDLLEEGIFNADDDSWKEQRRIIITEMHST---GFVEHSFQTTQHLVR 160

  Fly   169 K--LR-----AEDGRTFDCHDYMSEATVEILLETAMGVSKKT--QDKSGFEYAMAVMRMCDILHA 224
            |  |:     |:....||..|.....|.:|:....:|...:|  .|.....:|.|.....:....
plant   161 KKLLKVMESFAKSQEAFDLQDVFLRLTFDIICLAGLGADPETLAVDLPQVPFAKAFEEATESTLF 225

  Fly   225 RHRSIFLRNEFVFTLTRY----YKEQGRL-LNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAA 284
            |    |:...|::...|:    |::..|: :.::||...|:|..:             .||||
plant   226 R----FMIPPFIWKPMRFLDTGYEKGLRIAVGVVHGFVDKMIVDR-------------ICELK-- 271

  Fly   285 ALEREREQNGGVDQTPSTAGSDEKDREKDKEKASPVAGLSYGQSAGLKDDLDVE----DNDIGEK 345
              |.|...|                                 :|..|...:.:|    :|:| :.
plant   272 --EEETLDN---------------------------------RSDVLSRIIQIESHKRENEI-DP 300

  Fly   346 KRLAFLDLMLESAQNGALITDTEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELD 410
            ..:.|                  .::...:.:..|.||::...|:|..::..|.:::::::.|:.
plant   301 STIRF------------------FRQFCTSFILAGRDTSSVALSWFCWVIQKHPEVENKIICEIR 347

  Fly   411 SIF---GDSQRPATFQDTL-------EMKYLERCLMETLRMYPPVPLIARELQEDLKLNSGNYVI 465
            .|.   |||  |.:..::|       .|.||:..|.||||::||:|:..::..||..|..|.:|
plant   348 EILRQRGDS--PTSKNESLFTVKELNNMVYLQAALSETLRLFPPIPMEMKQAIEDDVLPDGTFV- 409

  Fly   466 PRGATVTVATVLLHRNPKVYANPNVFDPDNFLPER--QANR----HYYAFVPFSAGPRSCVGRKY 524
            .:|:.|..:...:.|...::..    |.:.|.|||  ||.:    ..:.:|.|:||||.|:|:.:
plant   410 RKGSRVYFSIYAMGRMESIWGK----DCEIFRPERWIQAGKFVSDDQFKYVVFNAGPRLCIGKTF 470

  Fly   525 AMLKLKILLSTILRNYRVYSDLTESDFKLQADII--------LKREEGFRVRLQPRT 573
            |.|::|::.:::|..|.:         |:..|.:        |..:.|.:|.:.||:
plant   471 AYLQMKMIAASVLLRYSI---------KVVQDHVIAPRVTTNLYMKYGLKVTITPRS 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	117/536 (22%)
CYP86C4	NP_172774.1	CYP86A	73..510	CDD:410687	110/529 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010