DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4g15 and CYP72A11

DIOPT Version :9

Sequence 1:	NP_572721.1	Gene:	Cyp4g15 / 32093	FlyBaseID:	FBgn0030304	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_188083.1	Gene:	CYP72A11 / 820693	AraportID:	AT3G14650	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	559	Identity:	125/559 - (22%)
Similarity:	232/559 - (41%)	Gaps:	136/559 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 LVLWYIY------W---RLSRAHLYRLAGRLPGPRGLPIVGHL---FDVIGPASS----VFRTVI 73
            :|.|:::      |   ::..::|.|..  |.|....|:||.|   |.:...|.|    :...:.
plant    16 VVSWWVWRTLQWVWFKPKMLESYLRRQG--LAGTPYTPLVGDLKKNFSMRAEARSKPINLTDDIT 78

  Fly    74 RKSAPFE-HIAK-------MWIGPKLVVFIYDPRDVELLLSSHVYIDKASEYKFFKPWLGDGLLI 130
            .:..|:. .:.|       .|.|....:.|.||..:..:|:......||..:...: .:..|:|.
plant    79 PRIVPYPLQMLKTHGRTFFTWFGAIPTITIMDPEQITEVLNKVYDFQKAHTFPLGR-LIATGVLS 142

  Fly   131 STGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVVRK-----LRAEDGRTFDCHDYMSEATVE 190
            ..|.||..||::|.|.|||..:|:.:..|:::...:|.|     ...|.....|....:...|.:
plant   143 YDGDKWAKHRRIINPAFHLEKIKNMVPAFHQSCSEIVCKWDKLVSDKESSCEVDVWPGLVSMTAD 207

  Fly   191 ILLETAMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTRYYKEQGRLLNIIHG 255
            ::..||.|.|                  |           :..:.:|.|      |..|..:|
plant   208 VISRTAFGSS------------------C-----------VEGQRIFEL------QAELAQLI-- 235

  Fly   256 LTTKVIRSKKAAFEQG-----TRGSLAQCELKAAALEREREQNGGVDQTPSTAGSDEKDREKDKE 315
                 |::.:.||..|     |:|:.   .:||.|.|.:....|.|         :::.|.::..
plant   236 -----IQTVRKAFIPGYSYLPTKGNR---RMKAKAREIQVILRGIV---------NKRLRAREAG 283

  Fly   316 KASPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLMLES---AQNGALITDTEIKEQVDTIM 377
            :|.             .|||               |.::|||   ...|..::..::.|:.....
plant   284 EAP-------------NDDL---------------LGILLESNLGQTKGNGMSTEDLMEECKLFY 320

  Fly   378 FEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQRPATFQDTLEMKYLERCLMETLRMY 442
            |.|.:||:....:.:.|:..|||.|.|...|:..:|||.:..|  :...::|.:...|.|.||:|
plant   321 FVGQETTSVLLVWTMVLLSQHQDWQARAREEVKQVFGDKEPDA--EGLNQLKVMTMILYEVLRLY 383

  Fly   443 PPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPER------Q 501
            ||:|.::|.:.::::|  |:..:|.|..:.:..:|:.|:.:::.|    |...|.|:|      :
plant   384 PPIPQLSRAIHKEMEL--GDLTLPGGVLINLPILLVQRDTELWGN----DAGEFKPDRFKDGLSK 442

  Fly   502 ANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNY 540
            |.::..:|.||:.|.|.|:|:.:|:|:.|:.::.||:.:
plant   443 ATKNQASFFPFAWGSRICIGQNFALLEAKMAMALILQRF 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	119/528 (23%)
CYP72A11	NP_188083.1	p450	24..512	CDD:299894	123/551 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.960