DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4g15 and CYP72A7

DIOPT Version :9

Sequence 1:	NP_572721.1	Gene:	Cyp4g15 / 32093	FlyBaseID:	FBgn0030304	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_188079.1	Gene:	CYP72A7 / 820689	AraportID:	AT3G14610	Length:	512	Species:	Arabidopsis thaliana

Alignment Length:	566	Identity:	135/566 - (23%)
Similarity:	229/566 - (40%)	Gaps:	140/566 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLLPTLVLWYIYWRLSR----------AHLYRLAGRLPGPRGLPIVGHL---FDVIGPASS---- 67
            :|:..:|||  .||:.:          :.|.|..  |.|....|:||.:   .|::..|.|
plant    11 VLVAVVVLW--TWRIVKWVWIKPKMLESSLKRQG--LTGTPYTPLVGDIKRNVDMMMEARSKPIN 71

  Fly    68 VFRTVIRKSAPFEHIAKM----------WIGPKLVVFIYDPRDVELLLSSHVYIDKASEYKFFKP 122
            |...:..:..|.  ..||          ||||...:.|.:|..::.:.:.....:|||.:...:
plant    72 VTDDITPRLLPL--ALKMLNSHGKTFFIWIGPLPTIVITNPEQIKEVFNKVNDFEKASTFPLIR- 133

  Fly   123 WLGDGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVV---RKL--RAEDGRTFDCHD 182
            .|..||....|.||.|||::|.|.|||..:|:.|..|......||   .||  ..|.....|...
plant   134 LLAGGLASYKGDKWASHRRIINPAFHLEKIKNMIPAFYHCCSEVVCQWEKLFTDKESPLEVDVWP 198

  Fly   183 YMSEATVEILLETAMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTRYYKEQG 247
            ::...|.:::..||.|.|                                          |||..
plant   199 WLVNMTADVISHTAFGSS------------------------------------------YKEGQ 221

  Fly   248 RLLNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALERERE--QNGGVDQTPSTAGSDEKDR 310
            |:..:...|...:.::.|.::..|:|....:...:..|::||.:  ..|.|.:           |
plant   222 RIFQLQGELAELIAQAFKKSYIPGSRFYPTKSNRRMKAIDREVDVILRGIVSK-----------R 275

  Fly   311 EKDKEKASPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLMLESAQ-----NGALITDTEIK 370
            ||.:|...|.           .|||               |.::|||..     ||..:.|  :.
plant   276 EKAREAGEPA-----------NDDL---------------LGILLESNSEESQGNGMSVED--VM 312

  Fly   371 EQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQRPATFQDTLEMKYLERCL 435
            ::.....|.|.:||:....:.:.|:..|||.|.|...|:..:.|::.:| ..:....:|.:....
plant   313 KECKLFYFAGQETTSVLLVWTMVLLSHHQDWQARAREEVMQVLGENNKP-DMESLNNLKVMTMIF 376

  Fly   436 METLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPER 500
            .|.||:||||..:.|.:.:::||  |...:|.|..:.:.|:|:.|:.:::.:    |..:|.|||
plant   377 NEVLRLYPPVAQLKRVVNKEMKL--GELTLPAGIQIYLPTILVQRDTELWGD----DAADFKPER 435

  Fly   501 ------QANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNY 540
                  :|.::..:|.||..|||.|:|:.:|||:.|:.::.||:.:
plant   436 FRDGLSKATKNQVSFFPFGWGPRICIGQNFAMLEAKMAMALILQKF 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	126/529 (24%)
CYP72A7	NP_188079.1	p450	21..512	CDD:299894	131/554 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.050