DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4g15 and CYP709B1

DIOPT Version :9

Sequence 1:	NP_572721.1	Gene:	Cyp4g15 / 32093	FlyBaseID:	FBgn0030304	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_566092.1	Gene:	CYP709B1 / 819310	AraportID:	AT2G46960	Length:	519	Species:	Arabidopsis thaliana

Alignment Length:	612	Identity:	135/612 - (22%)
Similarity:	240/612 - (39%)	Gaps:	160/612 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 FLLLPTLVLWYIYWRLSRA------HLYRLAGRL-----PGPRGLPIVGHL-----------FDV 61
            ||.|..|:| .|..|:.:|      |.:.|..||     .||......|:|           ..:
plant     6 FLALIVLIL-IIGLRIFKAFMILVWHPFVLTRRLKNQGISGPNYRIFYGNLSEIKKMKRESHLSI 69

  Fly    62 IGPASS-VFRTVIRKSAPFEHIAK----------MWIGPKLVVFIYDPRDVELLLSSHV--YIDK 113
            :.|:|: :|..::      .|..|          .|.|.:..:.|.||...:.:||:.:  ::..
plant    70 LDPSSNDIFPRIL------PHYQKWMSQYGETFLYWNGTEPRICISDPELAKTMLSNKLGFFVKS 128

  Fly   114 ASEYKFFKPWLGDGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVVRKLRAEDGRTF 178
            .:..:..|.....||:...|..|..||:::.|.|.::.||....:..:.:..::.:.|.|..:..
plant   129 KARPEAVKLVGSKGLVFIEGADWVRHRRILNPAFSIDRLKIMTTVMVDCTLKMLEEWRKESTKEE 193

  Fly   179 DCH--------DYMSEATVEILLETAMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEF 235
            ..|        :.....|.:|:..:|.|.|.    ..|.|...:.|.
plant   194 TEHPKIKKEMNEEFQRLTADIIATSAFGSSY----VEGIEVFRSQME------------------ 236

  Fly   236 VFTLTRYYKEQGRLLNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNGGVDQTP 300
               |.|.|......::|                 .||:.......::...|||:.:.:  :.:..
plant   237 ---LKRCYTTSLNQVSI-----------------PGTQYLPTPSNIRVWKLERKMDNS--IKRII 279

  Fly   301 STAGSDEKDREKDKEKASPVAGLSYGQSAGLKDDL--------DVEDNDIGEKKRLAFLDLMLES 357
            |:....:.|               ||      |||        :.|    |::::::.
plant   280 SSRLQSKSD---------------YG------DDLLGILLKAYNTE----GKERKMSI------- 312

  Fly   358 AQNGALITDTEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQRP--A 420
                     .||..:..|..|.||:||:...::...|:.:|||.|:::..|:....|..:.|  .
plant   313 ---------EEIIHECRTFFFGGHETTSNLLAWTTMLLSLHQDWQEKLREEIFKECGKEKTPDSE 368

  Fly   421 TFQDTLEMKYLERCLMETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVY 485
            ||.   ::|.:...:||:||:|.||..:|||...::||  |:..||:|.||.:..:.:|.:..::
plant   369 TFS---KLKLMNMVIMESLRLYGPVSALAREASVNIKL--GDLEIPKGTTVVIPLLKMHSDKTLW 428

  Fly   486 ANPNVFDPDNFLPERQAN------RHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYS 544
            .:    |.|.|.|.|.||      .|..|.:.||.|||:|:|:.:.|::.|.:|:.||:.:|..|
plant   429 GS----DADKFNPMRFANGVSRAANHPNALLAFSVGPRACIGQNFVMIEAKTVLTMILQRFRFIS 489

  Fly   545 DLTESDFKLQADIILKREEGFRVRLQP 571
            ...|.......::.::.:.|..|.|||
plant   490 LCDEYKHTPVDNVTIQPQYGLPVMLQP 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	115/542 (21%)
CYP709B1	NP_566092.1	p450	32..517	CDD:299894	126/585 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.050