DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4g15 and CYP86A8

DIOPT Version :9

Sequence 1:	NP_572721.1	Gene:	Cyp4g15 / 32093	FlyBaseID:	FBgn0030304	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_182121.1	Gene:	CYP86A8 / 819205	AraportID:	AT2G45970	Length:	537	Species:	Arabidopsis thaliana

Alignment Length:	610	Identity:	139/610 - (22%)
Similarity:	230/610 - (37%)	Gaps:	163/610 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 LLLPTLVLWYIYWR--LSRAHLYRLAGRLPGPRGLPIVGHL--------------FDVIGPASSV 68
            |::.:.:..|..|.  :||.        |.|||..||:|.|              .|.:...|..
plant     7 LMILSAITAYFLWLTFISRC--------LKGPRVWPILGSLPGLIENCERMHDWISDNLRACSGT 63

  Fly    69 FRTVIRKSAPFEHIAKMWIGPKLVVFIYDPRDVELLLSSHVYIDKASEYKFFKPW-------LGD 126
            ::|.| .:.||  :||.   ..||....|||::|     |:..::...|.....|       ||.
plant    64 YQTCI-CAIPF--LAKK---QGLVTVTCDPRNLE-----HILKNRFDNYPKGPTWQAVFHDLLGQ 117

  Fly   127 GLLISTGQKWRSHRKLIAPTFHLNVLKS-------------FIELFNENSRNVVRKLRAEDGRTF 178
            |:..|.|..|...||..|..|....|:.             |:.:. ||:|     |.:|   ..
plant   118 GIFNSDGDTWLFQRKTAALEFTTRTLRQAMARWVNRAIKLRFLPIL-ENAR-----LGSE---PI 173

  Fly   179 DCHDYMSEATVEILLETAMGVSKKTQDKSGF---EYAMAVMRMCDILHARHRSIFLRNEFVFTLT 240
            |..|.:...|.:.:.....|...:| ...|.   .:|:|..|..:....|    |:..|.::...
plant   174 DLQDLLLRLTFDNICGLTFGKDPRT-CAPGLPVNTFAVAFDRATEASLQR----FILPEILWKFK 233

  Fly   241 RYYKEQGRLLNIIHGLTTKVIRSKKAAFEQGTRGSLAQCE--LKAAALEREREQNGGVDQTPSTA 303
            |:.    ||     ||...:.|            ||.|.:  |......|:.|.     .|....
plant   234 RWL----RL-----GLEVSLTR------------SLVQVDNYLSEIITTRKEEM-----MTQHNN 272

  Fly   304 GSDEKDREKDKEKASPVAGLSYGQSAGLKDDLDVEDNDIGE--KKRLAFLDLMLESAQNGALITD 366
            |...                         |||      :..  ||:.::.|   |:.|..||
plant   273 GKHH-------------------------DDL------LSRFIKKKESYSD---ETLQRVAL--- 300

  Fly   367 TEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIF----GD-----SQRPATF 422
                    ..:..|.||::...|:|..|:..|..|:|::|.|:.::.    ||     :..|.:.
plant   301 --------NFILAGRDTSSVALSWFFWLITQHPAIEDKILREICTVLVETRGDDVALWTDEPLSC 357

  Fly   423 QDTLEMKYLERCLMETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYAN 487
            ::...:.:|:..|.||||:||.||..::...:|..|..|.:| |.|:::|.:.....|....:..
plant   358 EELDRLVFLKAALSETLRLYPSVPEDSKRAVKDDVLPDGTFV-PAGSSITYSIYSAGRMKSTWGE 421

  Fly   488 PNV-FDPDNFLPE----RQANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLT 547
            ..: |.|:.::.:    |..|...:.||.|:||||.|:|:..|.|::|.:.|.:|..:|: :.:|
plant   422 DCLEFKPERWISQSDGGRFINHDPFKFVAFNAGPRICLGKDLAYLQMKSIASAVLLRHRL-TVVT 485

  Fly   548 ESDFKLQADIILKREEGFRVRLQPR 572
            ....:.:..:.|..:.|..|.:..|
plant   486 GHKVEQKMSLTLFMKYGLLVNVHER 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	127/549 (23%)
CYP86A8	NP_182121.1	CYP86A	67..503	CDD:410687	120/533 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010