Protein Alignment Cyp4g15 and Cyp3a57

DIOPT Version :9

• Sequence 1: NP_572721.1
• Gene: Cyp4g15 / 32093
• FlyBaseID: FBgn0030304
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001093650.1
• Gene: Cyp3a57 / 622127
• MGIID: 3646373
• Length: 503
• Species: Mus musculus
• Alignment Length: 579
• Identity: 141/579 - (24%)
• Similarity: 259/579 - (44%)
• Gaps: 112/579 - (19%)

  Fly    18 YFLLLPTLVLWYIYWRLSRAHLYRLAGRLPGPRGLPIVGHLFDVIGPASSVFRTVIRKSAPFEHI 82
            :.||:.:||.:|||...|.. |::..| :|||:.||:.|::.:.:...........:|      .
Mouse    12 WVLLVTSLVFFYIYGTYSHG-LFKKLG-IPGPKPLPLFGNIINYLDGMWKFDDDCYKK------Y 68

  Fly    83 AKMW---IGPKLVVFIYDPRDVELLLSSHVYIDKASEYKFFKP--WLGDGLLISTGQKWRSHRKL 142
            .|:|   .||:.::.|.||..::::|....| ...:..:.|.|  :|...:.||..::|:..|.|
Mouse    69 GKIWGFYEGPQPILAIMDPEIIKIVLVKECY-SVFTNRRPFGPVGFLKKSITISEDEEWKRLRTL 132

  Fly   143 IAPTFHLNVLKSFIELFNENSRNVVRKLRAEDGR--TFDCHDYMSEATVEILLETAMGVS----K 201
            ::|||..:.||....:..:....:||.||.|:.:  ..:..|.....:::::..|:.||:    .
Mouse   133 LSPTFTSSKLKEMFPIMRQYGDILVRNLRREEEKEEPINMKDIFGAYSMDVITGTSCGVNIDSLN 197

  Fly   202 KTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFT-LTRYYKEQGRLLNIIHGLTTKVIRSKK 265
            ..||.       .|.::..||..:....||.:..:|. ||..|:    :||:
Mouse   198 NPQDP-------FVQKIKKILKFKFFDPFLLSVVLFPFLTPIYE----MLNL------------- 238

  Fly   266 AAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTAGSDEKDREKDKEKASPVAGLSYGQSAG 330
            :.|.:                           |:.:......|..:||:        |.|.|
Mouse   239 SIFPR---------------------------QSMNFFKKFVKKMKKDR--------LDYNQ--- 265

  Fly   331 LKDDLDVEDNDIGEKKRLAFLDLMLESAQNG------ALITDTEIKEQVDTIMFEGHDTTAAGSS 389
                          |.|:.||.||: :.||.      ..::|.|:..|....:|.|:|.|:...|
Mouse   266 --------------KNRVDFLQLMM-NTQNSKGQESLKALSDLEMAAQTLIFIFGGYDGTSTSIS 315

  Fly   390 FFLSLMGIHQDIQDRVLAELDSIFGDSQRPATFQDTLEMKYLERCLMETLRMYPPVPLIARELQE 454
            |.:..:..|.|:|.::..|:|... .::.|.|:...::|:||:..:.|:||:||.|..|.|..::
Mouse   316 FIMYELATHPDVQKKLQDEIDRAL-PNKAPVTYDALMDMEYLDMVVNESLRLYPVVSRIDRFSKK 379

  Fly   455 DLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPERQANRHYYAFVPFSAGPRSC 519
            |::::  ...||:|..|.:....|||:|:.:..|..|.|:.|..|.:.|...|.::||..|||:|
Mouse   380 DVEIH--GVFIPKGTIVMIPIYPLHRDPEYWPEPEDFCPERFSKENKGNIDPYIYMPFGNGPRNC 442

  Fly   520 VGRKYAMLKLKILLSTILRNYRVY-SDLTESDFKLQADIILKREE----GFRVRLQPRT 573
            :|.::|::.:|:.::.:|:|:.|. .:.|:...|:....|.:.|:    .|..|.:|||
Mouse   443 IGMRFALISVKLAVTGVLQNFTVQPCEETQIPVKISRQPIFRPEKPIILKFVSRDKPRT 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	121/512 (24%)
Cyp3a57	NP_001093650.1	p450	39..493	CDD:278495	126/540 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010