DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4g15 and Cyp4f17

DIOPT Version :9

Sequence 1:	NP_572721.1	Gene:	Cyp4g15 / 32093	FlyBaseID:	FBgn0030304	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_001178915.1	Gene:	Cyp4f17 / 500801	RGDID:	1561655	Length:	524	Species:	Rattus norvegicus

Alignment Length:	527	Identity:	148/527 - (28%)
Similarity:	257/527 - (48%)	Gaps:	81/527 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 GHLFDVIGPASSVFRTVIRKSAPFEHIAKMWIG---PKLVVFIYDPRDVELLLSSHVYI--DKAS 115
            ||| :::.......:.:...|..|:.|...|||   |  ::.:..|:.:..:|.:...:  .:..
  Rat    62 GHL-NLVKNNEEGLQLLAEMSHQFQDIHLCWIGIFYP--ILRLIHPKFIGPILQAPAAVAPKEMI 123

  Fly   116 EYKFFKPWLGDGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVV----RKLRAEDGR 176
            .|.|.|||||||||:|.|:||...|:|:.|.||.::||.:::.||: |.|::    ::|.|:...
  Rat   124 FYGFLKPWLGDGLLVSAGEKWSRQRRLLTPAFHFDILKPYVKNFNK-SVNIMHAKWQRLTAKGSA 187

  Fly   177 TFDCHDYMSEATVEILLETAMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTR 241
            ..|..:::|..|::.|.:.........|: |..||..|:..:..::..||...||..:|::.||.
  Rat   188 RLDMFEHISLMTLDSLQKCVFSFDSNCQE-SPSEYIAAIQELSSLIVKRHHQPFLYMDFLYYLTA 251

  Fly   242 YYKEQGRLLNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTAGSD 306
            ..:...:..:::|..|..|||                        ||.|        |.|:...|
  Rat   252 DGRRFRKACDLVHNFTDAVIR------------------------ERRR--------TLSSQSVD 284

  Fly   307 EKDREKDKEKASPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLD-LMLESAQNGALITDTEIK 370
            |..:.|.|.|.                              |.|:| |:|...::|..::|.:|:
  Rat   285 EFLKSKTKSKT------------------------------LDFIDVLLLAKDEHGKELSDEDIR 319

  Fly   371 EQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQ-RPATFQDTLEMKYLERC 434
            .:.||.||.||||||:..|:.|..:..|.:.|:|...|:..:..|.: ....:.|..::.:|..|
  Rat   320 AEADTFMFGGHDTTASALSWILYNLARHPEHQERCRQEVRELLRDREPEEIEWDDLTQLPFLTMC 384

  Fly   435 LMETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPE 499
            :.|:||::|||.:|:|...:|:.|..|. |||:|....::...:|.||.|:.:|.|:||..|..|
  Rat   385 IKESLRLHPPVTVISRCCTQDVVLPDGR-VIPKGNDCIISIFGVHHNPSVWPDPEVYDPFRFDSE 448

  Fly   500 RQANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTESDFKLQADIILKREEG 564
            ....|...||:|||||||:|:|:.:||.::|:.::..|..:|:..|  :.:.:.:.::||:.|.|
  Rat   449 NPQKRSPLAFIPFSAGPRNCIGQTFAMNEMKVAVALTLLRFRLLPD--DKEPRRKPELILRAEGG 511

  Fly   565 FRVRLQP 571
            ..:|::|
  Rat   512 LWLRVEP 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	140/496 (28%)
Cyp4f17	NP_001178915.1	p450	52..514	CDD:278495	146/521 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820