DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cyp4g15 and Cyp313a2

DIOPT Version :9

Sequence 1:	NP_572721.1	Gene:	Cyp4g15 / 32093	FlyBaseID:	FBgn0030304	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_650169.3	Gene:	Cyp313a2 / 41487	FlyBaseID:	FBgn0038006	Length:	493	Species:	Drosophila melanogaster

Alignment Length:	585	Identity:	151/585 - (25%)
Similarity:	251/585 - (42%)	Gaps:	122/585 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 VFYFLLLPTLVLWYIY-WRLSRAHLYRLAGRLPGPRGLPIVG----HLFDVIGPASSVFRTVIRK 75
            |...|:..:|:||..: |  ||..||.|..:|||..|||::|    :|....|..||  ||....
  Fly     3 VIQLLIAASLILWIRFLW--SRRKLYMLMMQLPGRMGLPLLGNSVRYLIISRGRMSS--RTTYMD 63

  Fly    76 SAPFEHIAKMWIGPKLVVFIYDPRDVELLLSSHVYIDKASE-YKFFKPWLGDGLLISTGQKWRSH 139
            .....::|  |||...:|...||:..|.:|:|...|:::|: .......:|.|||...|.||.:.
  Fly    64 KHGSTYMA--WIGTTPIVITRDPKIAEKVLTSPFCINRSSQTTNALALSMGYGLLTLQGSKWMAR 126

  Fly   140 RKLIAPTFHLNVLKSFIELFNENSRNVVRKLRAEDGRTFDC------HDYMSEA---TVEILLET 195
            ||.:.|.|..:||.||:.:||..:..:|        ..||.      .|.:|:.   :..|..:|
  Fly   127 RKHMNPAFKHSVLLSFLPIFNAETDLLV--------SVFDSFVGQGEKDVLSDLIRWSFAIATQT 183

  Fly   196 AMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSI---FLRNEFV---FTLTRYYKEQGRLLN-II 253
            .:|......|  .||....:.....:|.....:|   |::|:.|   |.|....:.....:| :|
  Fly   184 TLGTDVTKDD--NFENDAILKTYQSMLRLTIINIFVPFVQNKIVSKLFGLEWLRRRDASAINKMI 246

  Fly   254 HGLTTKVIRSKKAAFEQGTRGSLAQCELKAA---ALEREREQNGGVDQTPSTAGSDEKDREKDKE 315
            :.:..|.:.|....:        .:.|||..   |:|..|              :||
  Fly   247 NNILDKKLNSNPENY--------CESELKTVIHRAIELFR--------------NDE-------- 281

  Fly   316 KASPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLMLESAQNGALITDTEIKEQVDTIMFEG 380
                                               :.||             |:..:..:::...
  Fly   282 -----------------------------------MSLM-------------ELGAECSSMVLAA 298

  Fly   381 HDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQR-PATFQDTLEMKYLERCLMETLRMYPP 444
            .:|:|....:.|.|:.:..:.|:.|..|:...|..::. ..|..|..::.||:|.|.||||:.|.
  Fly   299 FETSAHTVYYALVLLAMFPEHQEMVFNEIKEHFPLAKGIEVTHTDLQQLVYLDRVLNETLRLMPS 363

  Fly   445 VPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNV-FDPDNFLPERQANRHYYA 508
            ||..:||..|||:|::| .|||:|.|:::......||...:.:... |:|:|||||:..:||.||
  Fly   364 VPFSSRETLEDLRLSNG-VVIPKGMTISIDIFNTQRNTDYWGSEAAQFNPENFLPEKIHDRHPYA 427

  Fly   509 FVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTESDFKLQADIILKREEGFRVRLQPRT 573
            |:|||.|.|:|:|.:|.::..|:.|..|||||::.:.....:.:....:::|..:..::..:.||
  Fly   428 FIPFSKGKRNCIGWRYGLMSSKLALVKILRNYKLKTSFPYENLEFVDHMVIKLAQSPQLAFERRT 492

Fly 574 573
Fly 493 492

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	136/520 (26%)
Cyp313a2	NP_650169.3	p450	33..463	CDD:299894	136/522 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I1543
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.860