Protein Alignment Cyp4g15 and CYP4X1

DIOPT Version :9

• Sequence 1: NP_572721.1
• Gene: Cyp4g15 / 32093
• FlyBaseID: FBgn0030304
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_828847.1
• Gene: CYP4X1 / 260293
• HGNCID: 20244
• Length: 509
• Species: Homo sapiens
• Alignment Length: 562
• Identity: 157/562 - (27%)
• Similarity: 258/562 - (45%)
• Gaps: 95/562 - (16%)

  Fly    21 LLPTLVLWYIYWRLSRAHLYRLAGRLPGPRGLPIVGHLFDVIGPASSVFRTVIRK---SAPFEHI 82
            ||..:.|:     |.|..|.|.....|.|.....:||...:..........:|.|   :.||
Human    26 LLQAIKLY-----LRRQRLLRDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEIIEKYPRAFPF--- 82

  Fly    83 AKMWIGPKLVVF-IYDPRDVELLLSSHVYIDKASEY--KFFKPWLGDGLLISTGQKWRSHRKLIA 144
               ||||....| ||||...:.|||.   .|..|:|  ||..|.||.||....|.||..||:|:.
Human    83 ---WIGPFQAFFCIYDPDYAKTLLSR---TDPKSQYLQKFSPPLLGKGLAALDGPKWFQHRRLLT 141

  Fly   145 PTFHLNVLKSFIELFNENSRNVV---RKLRAEDGRTFDCHDYMSEATVEILLETAMGVSKKTQDK 206
            |.||.|:||::||:...:.:.::   .|:.:....:.:.:::::..:::|:::.|.......|..
Human   142 PGFHFNILKAYIEVMAHSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCAFSKETNCQTN 206

  Fly   207 SGFE-YAMAVMRMCDILHARHRSIFLRNEFVFTLT-RYYKEQGRLLNIIHGLTTKVIRSKKAAFE 269
            |..: ||.|:..:..|:..|..|:...::.:|.|: :.|:.| :|..:::..|..:|:.:|.:.:
Human   207 STHDPYAKAIFELSKIIFHRLYSLLYHSDIIFKLSPQGYRFQ-KLSRVLNQYTDTIIQERKKSLQ 270

  Fly   270 QGTRGSLAQCELKAAALEREREQNGGVDQTPSTAGSDEKDREKDKEKASPVAGLSYGQSAGLKDD 334
            .|.:                      .|.||
Human   271 AGVK----------------------QDNTP---------------------------------- 279

  Fly   335 LDVEDNDIGEKKRLAFLDLMLESA-QNGALITDTEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIH 398
                     ::|...|||::|.:. ::|:..:|.::..:|.|.:..||||.||..|:.|..:.::
Human   280 ---------KRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTFLLAGHDTLAASISWILYCLALN 335

  Fly   399 QDIQDRVLAELDSIFGDSQRPATFQDTLEMKYLERCLMETLRMYPPVPLIARELQEDLKLNSGNY 463
            .:.|:|...|:..|.||.. ..|:....||.|...|:.||.|:.|.||.|:|:|.:.|....| .
Human   336 PEHQERCREEVRGILGDGS-SITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDG-C 398

  Fly   464 VIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPERQANRHYYAFVPFSAGPRSCVGRKYAMLK 528
            .:|.|.||.::...||.||.|:.||.||||..|..|....||.||::|||||.|:|:|:::||::
Human   399 TLPAGITVVLSIWGLHHNPAVWKNPKVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIE 463

  Fly   529 LKILLSTILRNYRVYSDLTESDFKLQADIILKREEGFRVRLQ 570
            ||:.::.||.::||..|.|. ........|||.:.|..:.|:
Human   464 LKVTIALILLHFRVTPDPTR-PLTFPNHFILKPKNGMYLHLK 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	141/506 (28%)
CYP4X1	NP_828847.1	p450	47..501	CDD:306555	149/531 (28%)
		heme binding region	447..460		7/12 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.920