DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp4g15 and Cyp4f17

DIOPT Version :9

Sequence 1:	NP_572721.1	Gene:	Cyp4g15 / 32093	FlyBaseID:	FBgn0030304	Length:	574	Species:	Drosophila melanogaster
Sequence 2:	NP_001094915.1	Gene:	Cyp4f17 / 208285	MGIID:	3646233	Length:	524	Species:	Mus musculus

Alignment Length:	525	Identity:	149/525 - (28%)
Similarity:	255/525 - (48%)	Gaps:	77/525 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 GHLFDVIGPASSVFRTVIRKSAPFEHIAKMWIGPKL-VVFIYDPRDVELLL--SSHVYIDKASEY 117
            ||: .::.......:.:..:|..|..:...||||.. ::.:..|:.:..:|  |:.|...:...|
Mouse    62 GHM-SMVKNNEEGLQLLTERSHQFHDVHLCWIGPFYPILRLIHPKFIGPILQASAAVAPKEMIFY 125

  Fly   118 KFFKPWLGDGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVV----RKLRAEDGRTF 178
            .|.|||||||||:|.|:||..||.|:.|.||.::||.:::.||: |.|::    ::|..:.....
Mouse   126 GFLKPWLGDGLLVSAGEKWSRHRHLLTPAFHFDILKPYMKNFNK-SVNIMHAKWQRLTTKGTACL 189

  Fly   179 DCHDYMSEATVEILLETAMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTRYY 243
            |..:::|..|::.|...........|: |..||..|:..:..::..||...||..:|::..|...
Mouse   190 DMLEHISLMTLDSLQNCVFSFDSNCQE-SPSEYIAAIQELSSLIVKRHHQPFLYLDFLYYCTADG 253

  Fly   244 KEQGRLLNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTAGSDEK 308
            :...:..:::|..|..|||                        ||.|        |.|:...||.
Mouse   254 RRFRKACDLVHNFTDAVIR------------------------ERRR--------TLSSQNLDEF 286

  Fly   309 DREKDKEKASPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLD-LMLESAQNGALITDTEIKEQ 372
            .:.|.|.|.                              |.|:| |:|...::|..::|.:|:.:
Mouse   287 LKSKTKSKT------------------------------LDFIDVLLLAKDEHGKELSDEDIRAE 321

  Fly   373 VDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIF-GDSQRPATFQDTLEMKYLERCLM 436
            .||.||.||||||:..|:.|..:..|.:.|:|...|:..:. |...:...:.|..::.:|..|:.
Mouse   322 ADTFMFGGHDTTASALSWILYNLARHPEYQERCRQEVQELLRGREPQEIEWDDLAQLPFLTMCIK 386

  Fly   437 ETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPERQ 501
            |:||::|||.:|:|...:|:.|..|. |||:|....::...:|.||:|:.:|.|:||..|.||..
Mouse   387 ESLRLHPPVTVISRCCTQDVVLPDGR-VIPKGTDCVISIFGVHHNPEVWPDPEVYDPFRFDPENP 450

  Fly   502 ANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTESDFKLQADIILKREEGFR 566
            ..|...||:|||||||:|:|:.:||.::|:.|:..|..:||...  :.:.:.:.::||:.|.|..
Mouse   451 QKRSPLAFIPFSAGPRNCIGQTFAMREMKVALALTLLRFRVLPG--DKEPRRKPELILRAEGGLW 513

  Fly   567 VRLQP 571
            :|::|
Mouse   514 LRVEP 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	141/494 (29%)
Cyp4f17	NP_001094915.1	p450	52..515	CDD:365848	147/520 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820