Protein Alignment Cyp4g15 and cyp-25A1

DIOPT Version :10

• Sequence 1: NP_572721.1
• Gene: Cyp4g15 / 32093
• FlyBaseID: FBgn0030304
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 610
• Identity: 130/610 - (21%)
• Similarity: 232/610 - (38%)
• Gaps: 169/610 - (27%)

  Fly    20 LLLPTLVL----WYIYWRLSRAHLYRLAGR--LPGPRGLPIVGHLFDVIGPASSVFRTVIRKSAP 78
            |:|.:||:    ::||..|:|...::|..:  |.||.....:|:|          .:|..||...
 Worm     4 LILSSLVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNL----------KQTAERKEKL 58

  Fly    79 FEHIAKMWI---------------GPKLVVFIYDPRDVELLLSSHVYIDKASEYK-------FFK 121
            ....|..|.               |.::.:.|.:.:|::     .|:|...|.:.       :..
 Worm    59 GYDDANRWFNELHEQYGETFGIYYGSQMNIVISNEKDIK-----EVFIKNFSNFSDRSVPSIYEA 118

  Fly   122 PWLGDGLLI-STGQKWRSHRKLIAPTFHLNVLKSFIELFNEN---SRNVVRKLRAEDGRTFDCHD 182
            ..|...||: |....|:..|..|||.|....:|:..|..|..   ..:::|: :|..|:.:|.:|
 Worm   119 NQLTASLLMNSYSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILRE-KASSGQKWDIYD 182

  Fly   183 YMSEATVEILLETAMGVSKKTQ-DKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTRYYKEQ 246
            .....|::::.:.|..:....| |::...|..|...:.:| ..||..|...:..:..|:.::|..
 Worm   183 DFQGLTLDVIGKCAFAIDSNCQRDRNDVFYVNAKKYISNI-DIRHSKIIAASVLLPELSTFWKAL 246

  Fly   247 GRL-------LNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTAG 304
            .:.       :.::.||:.                          ..||.|   ||       .|
 Worm   247 YKYTPLADAEIPLVEGLSN--------------------------VYERRR---GG-------EG 275

  Fly   305 SDEKD-------REKDKEKASPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLMLESAQNGA 362
            ||..|       ||.||.|.
 Worm   276 SDSVDLLKLLLNREDDKSKP--------------------------------------------- 295

  Fly   363 LITDTEIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQRPATFQDTLE 427
             :|..|:.|.....:..|::||:...::...|:..:.::|.::..|:  :........|:.....
 Worm   296 -MTKQEVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEI--MEAKENGGLTYDSIHN 357

  Fly   428 MKYLERCLMETLRMYPPV-PLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVF 491
            ||||:....||||.|||| ..|.|..:||:.:....|  |:||.|......:||||:.:.:|..|
 Worm   358 MKYLDCVYKETLRFYPPVIHFIRRLCREDITIRGQFY--PKGAIVVCLPHTVHRNPENWDSPEEF 420

  Fly   492 DPDNF--LPERQANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTESDFKLQ 554
            .|:.|  ..|:.::   ..::||..|||.|||.::|.::.|..:..:|..:.:      ..|:.:
 Worm   421 HPERFENWEEKSSS---LKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFEL------KQFEGE 476

  Fly   555 AD-------IILKREEGFRVRLQPR 572
            ||       :|::..:..|:.|:||
 Worm   477 ADLIPDCNGVIMRPNDPVRLHLKPR 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	CYP4	80..567	CDD:410721	109/537 (20%)
cyp-25A1	NP_497775.3	CYP3A-like	73..495	CDD:410678	107/523 (20%)