Protein Alignment Cyp4g15 and CYP4B1

DIOPT Version :9

• Sequence 1: NP_572721.1
• Gene: Cyp4g15 / 32093
• FlyBaseID: FBgn0030304
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_001093242.1
• Gene: CYP4B1 / 1580
• HGNCID: 2644
• Length: 512
• Species: Homo sapiens
• Alignment Length: 586
• Identity: 169/586 - (28%)
• Similarity: 277/586 - (47%)
• Gaps: 110/586 - (18%)

  Fly    13 PSSVFYFLLLPTLVLW------------YIYWRLSRAHLYRLAGRLPGPRGLPIVGHLFDVIGPA 65
            ||  |..|...:|.||            .|:..|.|..|.:...:.|||....:.||..::....
Human     3 PS--FLSLSFSSLGLWASGLILVLGFLKLIHLLLRRQTLAKAMDKFPGPPTHWLFGHALEIQETG 65

  Fly    66 SSVFRTVIRKSAPFEHIAKMWIGPKLVVF--IYDPRDVELLLSSHVYIDKASE-YKFFKPWLGDG 127
            |  ...|:..:..|.:...:|.| :.:.|  ||:|...:.:.|..  ..||.: |.||..|:|.|
Human    66 S--LDKVVSWAHQFPYAHPLWFG-QFIGFLNIYEPDYAKAVYSRG--DPKAPDVYDFFLQWIGRG 125

  Fly   128 LLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVVRKL--RAEDGRTFDCHDYMSEATVE 190
            ||:..|.||..||||:.|.||.:|||.::.:|.|::|.::.|.  :|.:|::||....:....:.
Human   126 LLVLEGPKWLQHRKLLTPGFHYDVLKPYVAVFTESTRIMLDKWEEKAREGKSFDIFCDVGHMALN 190

  Fly   191 ILL-------ETAMGVSKKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTRYYKEQGR 248
            .|:       :|.:|.|:   |.|   |.:||..:..::..|..|....|:|::.||.:.:...|
Human   191 TLMKCTFGRGDTGLGHSR---DSS---YYLAVSDLTLLMQQRLVSFQYHNDFIYWLTPHGRRFLR 249

  Fly   249 LLNIIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTAGSDEKDREKD 313
            ...:.|..|.:|||.:|||.:                                    |||.|:|
Human   250 ACQVAHDHTDQVIRERKAALQ------------------------------------DEKVRKK- 277

  Fly   314 KEKASPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLMLESA-QNGALITDTEIKEQVDTIM 377
                                        |..::.|.|||::|.:. ::...::|.:::.:|||.|
Human   278 ----------------------------IQNRRHLDFLDILLGARDEDDIKLSDADLRAEVDTFM 314

  Fly   378 FEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQRPATFQ--DTLEMKYLERCLMETLR 440
            |||||||.:|.|:||..|.::.:.|.|...|:..|.||..   .||  |..:|.||..|:.|:.|
Human   315 FEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQD---FFQWDDLGKMTYLTMCIKESFR 376

  Fly   441 MYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPERQANRH 505
            :|||||.:.|:|.:.:....|. .:|.|:.:::....||||..|:.:|.|||...|..|..:.||
Human   377 LYPPVPQVYRQLSKPVTFVDGR-SLPAGSLISMHIYALHRNSAVWPDPEVFDSLRFSTENASKRH 440

  Fly   506 YYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTESDFKLQADIILKREEGFRVRLQ 570
            .:||:|||||||:|:|:::||.::|::.:..|..:....|.:....|: ..::|:.:.||.:.|:
Human   441 PFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSRLPIKM-PQLVLRSKNGFHLHLK 504

  Fly   571 P 571
            |
Human   505 P 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	151/509 (30%)
CYP4B1	NP_001093242.1	p450	47..501	CDD:306555	156/534 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820