Protein Alignment Cyp4g15 and Cyp4a12b

DIOPT Version :10

• Sequence 1: NP_572721.1
• Gene: Cyp4g15 / 32093
• FlyBaseID: FBgn0030304
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Alignment Length: 593
• Identity: 160/593 - (26%)
• Similarity: 278/593 - (46%)
• Gaps: 121/593 - (20%)

  Fly     8 AALGS---PSSVF-YFLLLPTLVLWYIYWRLSRAHLYR-----LAGRLPGPRGLPIVGH------ 57
            :||.|   |.|:. |..:...|.|..:.::.::.:|:|     ...:.|.|....:.||
Mouse     4 SALSSIRFPGSISEYLQVASVLSLLLLLFKTAQLYLHRQWLLSSTQQFPSPPSHWLFGHKILKDQ 68

  Fly    58 -LFDVIGPASSVFRTVIRKSAPFEHIAKMWI-GPKLVVFIYDPRDVELLL-----SSHVYIDKAS 115
             |.|::        |.|:.   |......|: |.|:.:.:|||..::|:|     .:|      .
Mouse    69 DLQDIL--------TRIKN---FPSACPQWLWGSKVRIQVYDPDYMKLILGRSDPKAH------G 116

  Fly   116 EYKFFKPWLGDGLLISTGQKWRSHRKLIAPTFHLNVLKSFIELFNENSRNVVRKLRAEDGR--TF 178
            .|:|..||:|.|||:..||.|..||:::.|.||.::||.:.|:..::...::.|.....|:  |.
Mouse   117 SYRFLAPWIGRGLLLLDGQTWFQHRRMLTPAFHYDILKPYTEIMADSVHVMLDKWEQIVGQDSTL 181

  Fly   179 DCHDYMSEATVEILLETAMGVSKKTQ-DKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTRY 242
            :...:::..|::.:::.|.......| |:....|..||..:.::...|.|:||.:|:.::.::
Mouse   182 EIFQHITLMTLDTIMKCAFSHEGSVQLDRKYKSYIQAVEDLNNLFFLRVRNIFHQNDIIYRVS-- 244

  Fly   243 YKEQGRLLN----IIHGLTTKVIRSKKAAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTA 303
              ..|.|.|    :.|..|.:||:|:::..:
Mouse   245 --SNGCLANSACQLAHDHTDQVIKSRRSQLQ---------------------------------- 273

  Fly   304 GSDEKDREKDKEKASPVAGLSYGQSAGLKDDLDVEDNDIGEKKRLAFLDLML-ESAQNGALITDT 367
              ||::.||.|                             :|:||.|||::| ...:||..::|.
Mouse   274 --DEEELEKLK-----------------------------KKRRLDFLDILLFARMENGKSLSDK 307

  Fly   368 EIKEQVDTIMFEGHDTTAAGSSFFLSLMGIHQDIQDRVLAELDSIFGDSQRPATFQDTLEMKYLE 432
            :::.:|||.|||||||||:|.|:....:..:.:.|.|...|:.|:.||. ...|:.|..:|.|..
Mouse   308 DLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEIQSLLGDG-ASITWNDLDKMPYTT 371

  Fly   433 RCLMETLRMYPPVPLIARELQEDLKLNSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFL 497
            .|:.|.||:|||||.::|||...:....|. .:|:|..|.::...||.||.|:.||.||||..|.
Mouse   372 MCIKEALRIYPPVPSVSRELSSPVTFPDGR-SLPKGIHVMLSFYGLHHNPTVWPNPEVFDPSRFA 435

  Fly   498 PERQANRHYYAFVPFSAGPRSCVGRKYAMLKLKILLSTILRNYRVYSDLTESDFKLQADIILKRE 562
            |  .::||.::|:|||.|.|:|:|:::||.:||:.::..|..:.:..|.|.....:.. |:||.:
Mouse   436 P--GSSRHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRVPIPIPR-IVLKSK 497

  Fly   563 EGFRVRLQ 570
            .|..:.|:
Mouse   498 NGIHLHLK 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	CYP4	80..567	CDD:410721	140/500 (28%)
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	145/523 (28%)