Protein Alignment Cyp4g15 and CYP4F8

DIOPT Version :9

• Sequence 1: NP_572721.1
• Gene: Cyp4g15 / 32093
• FlyBaseID: FBgn0030304
• Length: 574
• Species: Drosophila melanogaster
• Sequence 2: NP_009184.1
• Gene: CYP4F8 / 11283
• HGNCID: 2648
• Length: 520
• Species: Homo sapiens
• Alignment Length: 568
• Identity: 167/568 - (29%)
• Similarity: 272/568 - (47%)
• Gaps: 82/568 - (14%)

  Fly    18 YFLLLPTLVLW----YIYWRLSRAHLYRLAGRLPGPRGLP-IVGHLFDVIGPASSVFRTVIRKSA 77
            :.|||.....|    .:.|..:..|..|.....|.||... .:||| .::.|.....|.:.:..|
Human    19 WLLLLVVGASWLLARILAWTYAFYHNGRRLRCFPQPRKQNWFLGHL-GLVTPTEEGLRVLTQLVA 82

  Fly    78 PFEHIAKMWIGP-KLVVFIYDPRDVELLL-SSHVYIDK-ASEYKFFKPWLGDGLLISTGQKWRSH 139
            .:......|:|| ..::.:..|..|..:: :|....|| ...||..|||||||||:|.|.|||.|
Human    83 TYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDKDIVFYKTLKPWLGDGLLLSVGDKWRHH 147

  Fly   140 RKLIAPTFHLNVLKSFIELFNENSRNVV----RKLRAEDGRTFDCHDYMSEATVEILLETAMGVS 200
            |:|:.|.||.|:||.:|::|:: |.|::    ::|..|.....|..:::|..|::.|.:......
Human   148 RRLLTPAFHFNILKPYIKIFSK-SANIMHAKWQRLAMEGSTCLDVFEHISLMTLDSLQKCIFSFD 211

  Fly   201 KKTQDKSGFEYAMAVMRMCDILHARHRSIFLRNEFVFTLTRYYKEQGRLLNIIHGLTTKVIRSKK 265
            ...|:|.. ||..|:|.:..::..|:...|...:|::.||...:...|...::|..|..||:
Human   212 SNCQEKPS-EYITAIMELSALVVKRNNQFFRYKDFLYFLTPCGRRFHRACRLVHDFTDAVIQ--- 272

  Fly   266 AAFEQGTRGSLAQCELKAAALEREREQNGGVDQTPSTAGSDEKDREKDKEKASPVAGLSYGQSAG 330
                                 ||.|        |.::.|.|:..:.|.|.|.
Human   273 ---------------------ERRR--------TLTSQGVDDFLQAKAKSKT------------- 295

  Fly   331 LKDDLDVEDNDIGEKKRLAFLD-LMLESAQNGALITDTEIKEQVDTIMFEGHDTTAAGSSFFLSL 394
                             |.|:| |:|...:||..::|.:|:.:.||.||.||||||:|.|:.|..
Human   296 -----------------LDFIDVLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYN 343

  Fly   395 MGIHQDIQDRVLAELDSIFGDSQ-RPATFQDTLEMKYLERCLMETLRMYPPVPLIARELQEDLKL 458
            :..|.:.|:|...|:..:..|.: :...:.|..::.:|..||.|:||::||:|..||...:|:.|
Human   344 LARHPEYQERCRQEVQELLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVL 408

  Fly   459 NSGNYVIPRGATVTVATVLLHRNPKVYANPNVFDPDNFLPERQANRHYYAFVPFSAGPRSCVGRK 523
            .... |||:|....:....:|.||.|:.:|.|:||..|.||....|...||:|||||||:|:|:|
Human   409 PDSR-VIPKGNVCNINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQK 472

  Fly   524 YAMLKLKILLSTILRNYRVYSDLTESDFKLQADIILKREEGFRVRLQP 571
            :||.::|::|:..|..:|:..|..|.  :...:|:|:.|:|..:|::|
Human   473 FAMAEMKVVLALTLLRFRILPDHREP--RRTPEIVLRAEDGLWLRVEP 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp4g15	NP_572721.1	p450	47..542	CDD:278495	151/504 (30%)
CYP4F8	NP_009184.1	p450	52..504	CDD:306555	154/519 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3B9GY
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	1	1.000	-	-		FOG0000016
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X23
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.820