Protein Alignment CG43155 and Kcnk9

DIOPT Version :10

• Sequence 1: NP_572720.2
• Gene: CG43155 / 32092
• FlyBaseID: FBgn0262685
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_445857.2
• Gene: Kcnk9 / 84429
• RGDID: 621451
• Length: 396
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 91/325 - (28%)
• Similarity: 137/325 - (42%)
• Gaps: 67/325 - (20%)

  Fly    66 IGLLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTILNNTEVHNLDELLSFEL 130
            :.|:.....|..||..:|..||...|:.....||  .:..|.|..:.|  :::.:...||:..:.
  Rat     9 LSLIACTFTYLLVGAAVFDALESDHEMREEEKLK--AEEVRLRGKYNI--SSDDYQQLELVILQS 69

  Fly   131 AKYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIVPVTTGGRVFCICF 195
            ..:.|.||                     |....:.:|:.||:||||||:..|.|..|:.||:.:
  Rat    70 EPHRAGVQ---------------------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFY 113

  Fly   196 ALIGIPFTLTVIADWGRLFATAVSVFGKHMP-------TKPKFTNFIGKTWFYAILAVGFLGVY- 252
            |::|||.||.:....|....|.|....|.:.       |:....|.:         .|||....
  Rat   114 AVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTEVSMENMV---------TVGFFSCMG 169

  Fly   253 -LAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGFGDLV--------PKKPNYMLLCTLYILIGLA 308
             |..||......| ||:||..:|:||||:|||||||.|        .:||.|:....:|||:||.
  Rat   170 TLCLGAAAFSQCE-DWSFFHAYYYCFITLTTIGFGDFVALQSKGALQRKPFYVAFSFMYILVGLT 233

  Fly   309 LTSTIIELVRRQYATSWAKLQELSGPMAETLRRLGETAGTGLDYTALQKVLTVSMPKWNSKKNEH 373
            :....:.||..::.|.......|.|.:|:.|      ||.       .:.:.|.:|:  |:|..|
  Rat   234 VIGAFLNLVVLRFLTMNTDEDLLEGEVAQIL------AGN-------PRRVVVRVPQ--SRKRHH 283

  Fly   374  373
              Rat   284  283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	143..214	CDD:462301	22/70 (31%)
		Ion_trans_2	<267..319	CDD:462301	26/59 (44%)
Kcnk9	NP_445857.2	Ion_trans_2	<73..132	CDD:462301	25/79 (32%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:Q9NPC2	93..98		4/4 (100%)
		Ion_trans_2	<184..243	CDD:462301	25/58 (43%)
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:Q9NPC2	199..204		4/4 (100%)
		X-gate. /evidence=ECO:0000250|UniProtKB:Q9NPC2	243..248		0/4 (0%)