DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43155 and KCNK16

DIOPT Version :9

Sequence 1:NP_572720.2 Gene:CG43155 / 32092 FlyBaseID:FBgn0262685 Length:411 Species:Drosophila melanogaster
Sequence 2:NP_001128577.1 Gene:KCNK16 / 83795 HGNCID:14464 Length:322 Species:Homo sapiens


Alignment Length:254 Identity:75/254 - (29%)
Similarity:116/254 - (45%) Gaps:50/254 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    52 ACWQSMKWKSALNHIGLLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFL--HTIL 114
            :||..       ..:.||::...|..:|..||:.|||.||.:.    :|..:..:.|||  :|.|
Human     8 SCWGG-------RVLPLLLAYVCYLLLGATIFQLLERQAEAQS----RDQFQLEKLRFLENYTCL 61

  Fly   115 NNTEVHNLDELLSFELAKYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGYG 179
            :...:              |..||...|..:..|..|........|....:.||:.||:||||||
Human    62 DQWAM--------------EQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYG 112

  Fly   180 NIVPVTTGGRVFCICFALIGIPFTLTVIADWG---RLFATAVSVFGKHMPTKPKFTNFIGKTWFY 241
            |:.|.|..|:|||:.:||:|||..:..:...|   |....|:    :....:|:.:.        
Human   113 NLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAI----ERWEDRPRRSQ-------- 165

  Fly   242 AILAVGFLGVYLAAGAGLLLLWE-------DDWTFFDGFYFCFITMTTIGFGDLVPKKP 293
             :|.|..|.::|..|..::|::.       :.|:|.:||||.|||::||||||.|...|
Human   166 -VLQVLGLALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGHP 223

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43155NP_572720.2 Ion_trans_2 <157..214 CDD:285168 25/59 (42%)
Ion_trans <240..314 CDD:278921 23/61 (38%)
Ion_trans_2 <266..319 CDD:285168 17/28 (61%)
KCNK16NP_001128577.1 Ion_trans_2 <92..148 CDD:311712 24/55 (44%)
Ion_trans_2 180..>224 CDD:311712 18/44 (41%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1418
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000030
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11003
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X19
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
54.910

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