Protein Alignment CG43155 and Kcna6

DIOPT Version :10

• Sequence 1: NP_572720.2
• Gene: CG43155 / 32092
• FlyBaseID: FBgn0262685
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_076444.1
• Gene: Kcna6 / 64358
• RGDID: 62083
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 228
• Identity: 52/228 - (22%)
• Similarity: 82/228 - (35%)
• Gaps: 77/228 - (33%)

  Fly    38 GGLAKG------TAGGR-----------------------RSTAC-WQSMKWKSALNHIGLLVSL 72
            |||..|      |.||.                       |.:|| .::..:::.:|.|.|:...
  Rat   242 GGLGTGGTSSFSTLGGSFFTDPFFLVETLCIVWFTFELLVRFSACPSKAAFFRNIMNIIDLVAIF 306

  Fly    73 SIYCGVG-GLIFRHLERPA-----------------EVERLSHLKDIVKTHRERFLHTILNNTEV 119
            ..:..:| .|:.||.::|.                 .|.||..:..|.|..|......||..|..
  Rat   307 PYFITLGTELVQRHEQQPVSGGSGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQ 371

  Fly   120 HNLDEL-----------LSFELAKYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVL 173
            .::.||           :.|..|.|.|....         .|..||      ||..|.:::...:
  Rat   372 ASMRELGLLIFFLFIGVILFSSAVYFAEADD---------VDSLFP------SIPDAFWWAVVTM 421

  Fly   174 TTIGYGNIVPVTTGGRVFCICFALIGIPFTLTV 206
            ||:|||::.|:|.||::.....|:.|:   ||:
  Rat   422 TTVGYGDMYPMTVGGKIVGSLCAIAGV---LTI 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	143..214	CDD:462301	19/64 (30%)
		Ion_trans_2	<267..319	CDD:462301
Kcna6	NP_076444.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35
		BTB_POZ_KCNA6	41..170	CDD:349714
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..239
		Ion_trans	258..469	CDD:459842	45/212 (21%)
		S4-S5 linker. /evidence=ECO:0000250|UniProtKB:P63142	361..374		3/12 (25%)
		Selectivity filter. /evidence=ECO:0000250|UniProtKB:P63142	423..428		3/4 (75%)
		PDZ-binding. /evidence=ECO:0000255	527..529