Protein Alignment CG43155 and Kcnk13

DIOPT Version :10

• Sequence 1: NP_572720.2
• Gene: CG43155 / 32092
• FlyBaseID: FBgn0262685
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_071629.2
• Gene: Kcnk13 / 64120
• RGDID: 68941
• Length: 405
• Species: Rattus norvegicus
• Alignment Length: 311
• Identity: 90/311 - (28%)
• Similarity: 137/311 - (44%)
• Gaps: 64/311 - (20%)

  Fly    67 GLLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTILNNTEVHNL--DELLSFE 129
            ||::   :|...|..:|..||...|::.           ::|:...:.|.:..|||  :||..|
  Rat    25 GLIL---LYLLGGAAVFSALELAQELQA-----------KQRWEERLANFSRGHNLSREELRGF- 74

  Fly   130 LAKYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIVPVTTGGRVFCIC 194
            |..||    :|.:.|:.:    |...|  ||....|.:|..||:||||:|...|.||||:||.|.
  Rat    75 LRHYE----EATKAGIRM----DSVRP--RWDFTGAFYFVGTVVTTIGFGMTTPATTGGKVFLIF 129

  Fly   195 FALIGIPFT-----------LTVIA--------DWGRLFATAVSVFGKHMPTKPKFTNFIGKTW- 239
            :.|||...|           :||||        ...|...|.....|| .|.|.:..:..|  |
  Rat   130 YGLIGCASTILFFNLFLERLITVIAYVMRTCHHQQLRRRGTVARDNGK-APRKGEADSLAG--WK 191

  Fly   240 ---FYAILAVGFLGVYLAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGFGDLVPKKPN------- 294
               :|.:|.:....|.::.||..|....:.|::||..||||:..:||||||||..:..
  Rat   192 PSVYYVMLILCLASVAISCGASALYTTMEGWSYFDSVYFCFVAFSTIGFGDLVSSQNAQYENEGL 256

  Fly   295 YMLLCTLYILIGLALTST---IIELVRRQYATSWAKLQELSGPMAETLRRL 342
            |..:...:||:|:....:   :|.::.:| ..:|...:..||...:..|.|
  Rat   257 YRFVNFFFILMGVCCIYSMFNVISILIKQ-TVNWILRKLDSGCFPQCQRGL 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	143..214	CDD:462301	31/89 (35%)
		Ion_trans_2	<267..319	CDD:462301	20/61 (33%)
Kcnk13	NP_071629.2	Ion_trans_2	84..150	CDD:462301	26/71 (37%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:P57789	110..115		3/4 (75%)
		Ion_trans_2	203..285	CDD:462301	24/81 (30%)
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:P57789	237..242		4/4 (100%)