DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG43155 and kcnk3a

DIOPT Version :9

Sequence 1:	NP_572720.2	Gene:	CG43155 / 32092	FlyBaseID:	FBgn0262685	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001025333.1	Gene:	kcnk3a / 561866	ZFINID:	ZDB-GENE-040724-171	Length:	390	Species:	Danio rerio

Alignment Length:	308	Identity:	89/308 - (28%)
Similarity:	136/308 - (44%)	Gaps:	64/308 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 LLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTILNNTEVHNLDEL--LSFEL 130
            |::....|..||..:|..||...|:.:...|.|     |:|.|....|.::| |.|||  :..:|
Zfish    11 LIICTFTYLLVGAAVFDALESKMEITQKKILDD-----RKRELMDKYNLSKV-NFDELERVVLQL 69

  Fly   131 AKYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIVPVTTGGRVFCICF 195
            ..::|.||                     |....:.:|:.||:||||||:..|.|.||:|||:.:
Zfish    70 KPHKAGVQ---------------------WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFY 113

  Fly   196 ALIGIPFTLTVIADWGRLFATAVSVFGKHM-----------PTKPKFTNFIGKTWFYAILAVGFL 249
            ||:|||.||.:....|.    .::.|.|::           .|:....|.:         .:|.:
Zfish   114 ALLGIPLTLVMFQSLGE----RINTFVKYLLHRLKKCLGLRHTEVSMANMV---------CIGLI 165

  Fly   250 GVY--LAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGFGDLV--------PKKPNYMLLCTLYIL 304
            ...  |..||.....:| ||:||..:|:||||:|||||||.|        ...|.|:....:|||
Zfish   166 SCMSTLCVGAAAFSRYE-DWSFFHAYYYCFITLTTIGFGDYVALQKDNALQTNPQYVAFSFMYIL 229

  Fly   305 IGLALTSTIIELVRRQYATSWAKLQELSGPMAETLRRLGETAGTGLDY 352
            .||.:....:.||..::.|..|:.:.........|.|..::.|.|.::
Zfish   230 TGLTVIGAFLNLVVLRFMTMNAEDERRDAEQRTLLSRNRQSGGAGTNH 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	<157..214	CDD:285168	25/56 (45%)
		Ion_trans	<240..314	CDD:278921	29/83 (35%)
		Ion_trans_2	<266..319	CDD:285168	26/60 (43%)
kcnk3a	NP_001025333.1	Ion_trans_2	<77..132	CDD:285168	26/79 (33%)
kcnk3a	NP_001025333.1	Ion_trans_2	165..247	CDD:285168	30/82 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910