Protein Alignment CG43155 and kcnb1

DIOPT Version :10

• Sequence 1: NP_572720.2
• Gene: CG43155 / 32092
• FlyBaseID: FBgn0262685
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: XP_682848.4
• Gene: kcnb1 / 555284
• ZFINID: ZDB-GENE-090831-3
• Length: 834
• Species: Danio rerio
• Alignment Length: 510
• Identity: 111/510 - (21%)
• Similarity: 177/510 - (34%)
• Gaps: 198/510 - (38%)

  Fly    40 LAKGTAG----GRRSTACWQSMKWKSALNHIGLLVSLSIY----CGVGGL----IFRHLERPAEV 92
            :.|.:||    |.||||....       ..:.::.|:|.|    ..||||    ::|.|:|....
Zfish     1 MEKPSAGMSKVGSRSTASLPP-------EPVDIIRSMSCYRRVKLNVGGLPHEVLWRTLDRLPRT 58

  Fly    93 ERLSHLKDIVKTH--------------RERFLH-------TILN---NTEVHNLDEL--LSF--E 129
             ||..|:| .|||              .|.|..       :|||   ..::|.::|:  |||  |
Zfish    59 -RLGKLRD-CKTHESLMEVCDDYNLEDNEYFFDRHPGAFTSILNFYRTGKLHMMEEMCALSFSQE 121

  Fly   130 L---------------AKYEAAVQQAAEGGLLIVAD--KDFP-EPYER----------WSILQ-- 164
            |               |:|....:|..| .|...||  ||.. |.::.          |.:|:
Zfish   122 LDYWGVDEIYLESCCQARYHQKKEQMNE-ELKREADTLKDREGEEFDNTCCSEKRKKLWDLLEKP 185

  Fly   165 ------------AVFFSSTVLTTIG--------------YGNIVPVTTGGRVFCICFALIGIPFT 203
                        ::.|  .||:||.              :|.....|....|..:|.|...:.:.
Zfish   186 GSSVAAKILAIISILF--IVLSTIALSLNTLPELQETDEFGQTTDNTQLAHVEAVCIAWFTMEYL 248

  Fly   204 LTVIAD---WGRLFATAVSVFG--------------KHMPTKPKFTNFIGKTWFYAILAV----- 246
            |..::.   | :.|...::|..              :...:..:|.|.......:.|:.:
Zfish   249 LRFLSSPNKW-KFFKGPLNVIDLLAILPYYVTIFLTESNKSVLQFQNVRRVVQIFRIMRILRILK 312

  Fly   247 ----------------------GFLGVYLAAGAGL---LLLW----EDDWTFFD---GFYFCFIT 279
                                  |.|.::||.|..:   |:.:    |||..|..   .|::..||
Zfish   313 LARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIFSSLVFFAEKDEDDTKFKSIPASFWWATIT 377

  Fly   280 MTTIGFGDLVPKKPNYML------LCTLYILIGLALTSTII---------------ELVRRQYAT 323
            |||:|:||:.||.   :|      ||.:..::.:||...||               :.::|:.|.
Zfish   378 MTTVGYGDIYPKT---LLGKIVGGLCCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRREAL 439

  Fly   324 SWAKLQELSGPMAETLRRLGETAGTG-LDYTALQK-------VLTVSMPKWNSKK 370
            ..||   .:|.:.....|...:.||. ||...:.|       .|:.|..||:||:
Zfish   440 ERAK---RNGSIVSMNVREAFSRGTDLLDVVVMDKGERSQDNHLSPSRWKWSSKR 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	143..214	CDD:462301	20/114 (18%)
		Ion_trans_2	<267..319	CDD:462301	19/75 (25%)
kcnb1	XP_682848.4	BTB_POZ_KCNB1	25..141	CDD:349718	30/117 (26%)
		Ion_trans	191..427	CDD:459842	45/241 (19%)
		Kv2channel	470..712	CDD:397541	7/22 (32%)