DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG43155 and kcnk5b

DIOPT Version :9

Sequence 1:	NP_572720.2	Gene:	CG43155 / 32092	FlyBaseID:	FBgn0262685	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_956927.1	Gene:	kcnk5b / 393606	ZFINID:	ZDB-GENE-040426-1297	Length:	448	Species:	Danio rerio

Alignment Length:	266	Identity:	86/266 - (32%)
Similarity:	122/266 - (45%)	Gaps:	55/266 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 LLVSLSI-YCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTILNNTEVHNLDELLSFELA 131
            :|.|:.| |..:|..||:.||.|       :|...|..::.:          .:||       |.
Zfish     7 ILTSVIIFYLSIGAAIFQILEEP-------NLNSAVDDYKNK----------TNNL-------LK 47

  Fly   132 KYEA-----------AVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIVPVT 185
            ||..           .|.:|...|:.:..:..|    ..|:...||.|::||:|||||||:.|.|
Zfish    48 KYPCLSKEVLGEIIEVVAEATGQGVTVTKEAQF----NNWNWENAVIFAATVITTIGYGNVAPKT 108

  Fly   186 TGGRVFCICFALIGIPFTLTVIADWGRLFATAVSVFGK---HMPTKPKFTNFIGKTWFYAILAVG 247
            ||||:|||.:.|.|||..||.|::.|..|.:......:   |.....:...||....|   |..|
Zfish   109 TGGRLFCILYGLCGIPLCLTWISELGTFFGSRTKRLSQLLLHSGLNVRKVQFICTIVF---LLWG 170

  Fly   248 FLGVYLAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGFGDLVP------KKPN-YMLLCTLYILI 305
            || |:|...|.:.:.:| :||:.:|.||.|.|:||:||||.|.      ..|. |.....|:|.:
Zfish   171 FL-VHLIIPAFVFMFFE-NWTYLEGLYFSFTTLTTVGFGDYVAGVDPSVNYPTLYRFFVQLWIYL 233

  Fly   306 GLALTS 311
            |||..|
Zfish   234 GLAWLS 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	<157..214	CDD:285168	30/56 (54%)
		Ion_trans	<240..314	CDD:278921	31/79 (39%)
		Ion_trans_2	<266..319	CDD:285168	22/53 (42%)
kcnk5b	NP_956927.1	Ion_trans_2	<81..137	CDD:285168	30/55 (55%)
		Ion_trans	<142..234	CDD:278921	30/96 (31%)
		Ion_trans_2	171..243	CDD:285168	28/71 (39%)
		C_Hendra	258..>323	CDD:293426
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	71	1.000	Domainoid score	I9409
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.910