Protein Alignment CG43155 and Kcnk18

DIOPT Version :9

• Sequence 1: NP_572720.2
• Gene: CG43155 / 32092
• FlyBaseID: FBgn0262685
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_997144.1
• Gene: Kcnk18 / 332396
• MGIID: 2685627
• Length: 394
• Species: Mus musculus
• Alignment Length: 380
• Identity: 88/380 - (23%)
• Similarity: 139/380 - (36%)
• Gaps: 138/380 - (36%)

  Fly    69 LVSLSIYCGVGGLIFRHLE-RP-AEVERLSHLKDIVKTHRERFLHTILNNTEVHNLDELLSFELA 131
            |..|..|..||..:|..:| || .|.|....||        :||..:.|         :|...|.
Mouse    38 LCCLVTYALVGAALFSAVEGRPDPEAEENPELK--------KFLDDLCN---------ILKCNLT 85

  Fly   132 KYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIVPVTTGGRVFCICFA 196
            ..|.:.:...| .|..:..:....|.: ||.|.|:||..||.:|:|||::.|||..|:..|:.:|
Mouse    86 VVEGSRKNLCE-HLQHLKPQWLKAPQD-WSFLSALFFCCTVFSTVGYGHMYPVTRLGKFLCMLYA 148

  Fly   197 LIGIPFTLTVIADWGRLFATAVS------------------------------------------ 219
            |.|||....|:.|.|.:.||.:|
Mouse   149 LFGIPLMFLVLTDIGDILATILSRAYSRFQALLCLPHDIFKWRSLPLCRKQPDSKPVEEAIPQIV 213

  Fly   220 -------------------------VFGK----------HMPTKPKFTNFIGKTWFYAILAVGFL 249
                                     :|.:          ..||:|     :.::.....|.:|.|
Mouse   214 IDAGVDELLNPQPSKDPPSPSCNVELFERLVAREKKNKLQPPTRP-----VERSNSCPELVLGRL 273

  Fly   250 G-----------------------------VYLAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGF 285
            .                             .|::..|.:|..||.:..|.|.|||||:|:|||||
Mouse   274 SCSILSNLDEVGQQVERLDIPLPVIALVVFAYISCAAAILPFWETELGFEDAFYFCFVTLTTIGF 338

  Fly   286 GDLVPKKPNYMLLCTLYILIGLALTSTIIELVRRQYATSWAKL------QELSGP 334
            ||:|...|::.|..::||::|:.:.....:|::.:...::..|      :|:|.|
Mouse   339 GDIVLVHPHFFLFFSIYIIVGMEILFIAFKLMQNRLLHTYKTLMLFVCQREVSLP 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	<157..214	CDD:285168	25/56 (45%)
		Ion_trans	<240..314	CDD:278921	29/102 (28%)
		Ion_trans_2	<266..319	CDD:285168	22/52 (42%)
Kcnk18	NP_997144.1	Ion_trans_2	<111..166	CDD:285168	25/55 (45%)
		Interaction with calcineurin	210..215		0/4 (0%)
		Interaction with YWHAH. /evidence=ECO:0000269|PubMed:18397886	261..266		0/4 (0%)
		Ion_trans_2	300..376	CDD:285168	27/75 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845577
Domainoid	1	1.000	68	1.000	Domainoid score	I9706
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840