Protein Alignment CG43155 and Kcnk12

DIOPT Version :10

• Sequence 1: NP_572720.2
• Gene: CG43155 / 32092
• FlyBaseID: FBgn0262685
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_954859.1
• Gene: Kcnk12 / 210741
• MGIID: 2684043
• Length: 430
• Species: Mus musculus
• Alignment Length: 414
• Identity: 111/414 - (26%)
• Similarity: 164/414 - (39%)
• Gaps: 117/414 - (28%)

  Fly    60 KSALNH-----IGLLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTILNNTEV 119
            :|.||.     :.|...:.:|...|..:|..||.|.|.|.           |.|:..|:.|.:..
Mouse    29 RSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEA-----------RARWGATLRNFSAA 82

  Fly   120 HNL--DELLSFELAKYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIV 182
            |.:  .||.:| |..||||:   |.|   :.||...|    ||....|.:|..||::|||:|...
Mouse    83 HGVAEPELRAF-LRHYEAAL---AAG---VRADALRP----RWDFPGAFYFVGTVVSTIGFGMTT 136

  Fly   183 PVTTGGRVFCICFALIGIPFTLTV-----------------------IADWGRLFAT-----AVS 219
            |.|.||:.|.|.:.|.|...|:..                       :...|.|.||     |:|
Mouse   137 PATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALS 201

  Fly   220 VFGKHMPTKPKFTNFIGKTWFYAILAVGFLGVYLAAGAGLLLLWEDDWTFFDGFYFCFITMTTIG 284
            ........||..        ::.:|.:|...|.||..|..:....:.|.:.|..||||:|.:|||
Mouse   202 EADSLAGWKPSV--------YHVLLILGLFAVLLACCASAMYTSVEGWDYVDSLYFCFVTFSTIG 258

  Fly   285 FGDLVPKKPN-------YMLLCTLYILIGL----ALTSTIIELVRRQYATSWAKLQELS------ 332
            |||||..:..       |.|...|:||:|:    :|.:.|..|:::  ..:| .|::||
Mouse   259 FGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQ--VLNW-MLRKLSCRCCTR 320

  Fly   333 ---GPMAETLRRLGETAGTGL--------------DYTALQKVLT---VSMPKWNSKKNEHSPDI 377
               .|.|...||...|.|:.|              |..|..:.|:   :||           .|:
Mouse   321 CCPAPGAPLARRNAITPGSRLRRRLAALGADPATRDSDAEGRRLSGELISM-----------RDL 374

  Fly   378 AALEAITNAIL-KEVKEAQNNKPK 400
            .|...::.|:| |::.|..|..|:
Mouse   375 TASNKVSLALLQKQLSETANGYPR 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	143..214	CDD:462301	24/93 (26%)
		Ion_trans_2	<267..319	CDD:462301	24/62 (39%)
Kcnk12	NP_954859.1	Ion_trans_2	100..169	CDD:462301	25/78 (32%)
		Ion_trans_2	222..304	CDD:462301	28/81 (35%)