Protein Alignment CG43155 and twk-7

DIOPT Version :10

• Sequence 1: NP_572720.2
• Gene: CG43155 / 32092
• FlyBaseID: FBgn0262685
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_498903.3
• Gene: twk-7 / 192073
• WormBaseID: WBGene00006662
• Length: 557
• Species: Caenorhabditis elegans
• Alignment Length: 321
• Identity: 100/321 - (31%)
• Similarity: 154/321 - (47%)
• Gaps: 56/321 - (17%)

  Fly    60 KSALNHIGLLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTIL-----NNTE- 118
            |..|.|:.|::....|..:|.|||..:|:|.|.........::.|.:..|:..::     |.|:
 Worm   160 KLVLPHVALVLLTCTYTVIGALIFYSVEQPHEQMMKEQQLKLIYTRQNEFVDDLIRLAAGNETKR 224

  Fly   119 ----------VHNLDELLSFELAKYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVL 173
                      :||:.:.|.....||.....:..:....           |.|:...::||:.||:
 Worm   225 YEWESLAERHMHNMSDQLFVAFEKYFLTSNEVKKNAAT-----------ETWTFSSSIFFAVTVV 278

  Fly   174 TTIGYGNIVPVTTGGRVFCICFALIGIPFTLTVIADWGRLFAT-AVSVFGKHMPTKPKFTN---- 233
            |||||||.||||..||::||.|:|:|||.||..|||.|:..:. .|.::|.::..|....:
 Worm   279 TTIGYGNPVPVTNIGRIWCILFSLLGIPLTLVTIADLGKFLSEHLVWLYGNYLKLKYLILSRHRK 343

  Fly   234 -------------------FIGKTWFYAILAVGFLGVYLAAGAGLLLLWEDDWTFFDGFYFCFIT 279
                               .|.:....|.|.:..|.||.|.| |:|:...:.|:||..||:.|||
 Worm   344 ERREHVCEHCHSHGMGHDMNIEEKRIPAFLVLAILIVYTAFG-GVLMSKLEPWSFFTSFYWSFIT 407

  Fly   280 MTTIGFGDLVPKKPNYMLLCTLYILIGLALTSTIIELVRRQYATS----WAKLQELSGPMA 336
            |||:|||||:|::..||.:..|||::|||:|:..|:||..||...    ..|:|:....:|
 Worm   408 MTTVGFGDLMPRRDGYMYIILLYIILGLAITTMCIDLVGVQYIRKIHYFGRKIQDARSALA 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	143..214	CDD:462301	32/70 (46%)
		Ion_trans_2	<267..319	CDD:462301	29/51 (57%)
twk-7	NP_498903.3	Ion_trans_2	<265..321	CDD:462301	31/55 (56%)
		Ion_trans_2	373..>422	CDD:462301	25/49 (51%)