Protein Alignment CG43155 and twk-37

DIOPT Version :10

• Sequence 1: NP_572720.2
• Gene: CG43155 / 32092
• FlyBaseID: FBgn0262685
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_491810.2
• Gene: twk-37 / 183583
• WormBaseID: WBGene00006689
• Length: 382
• Species: Caenorhabditis elegans
• Alignment Length: 344
• Identity: 84/344 - (24%)
• Similarity: 151/344 - (43%)
• Gaps: 49/344 - (14%)

  Fly     3 MKKVTVKEYDSQDEASTELLEK---LKHLDRRVDAAEGGGLAKGTAGGRRSTACWQSMKWKSALN 64
            :.|...::.:.....:..|:.|   ||.::|           |..|...:.|.....::.....|
 Worm    41 INKFIKRQMEKSSPETQHLVRKQSILKFVER-----------KSRAERPKPTKLRTILRKIRKFN 94

  Fly    65 HIGLLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTILNNTEVHNLDELLSFE 129
            .|...|.|..|...|.|:|..:|..:::    ::.:..:..|::.:| |.|:.:.....:|...:
 Worm    95 TIIAFVVLVAYIIGGALLFWQIESRSDM----NINEFKRNIRQKSIH-IYNSMKGSKCGKLKKAD 154

  Fly   130 LAKYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIVPVTTGGRVFCIC 194
            .......:::..:   |:.|... |:..|.:  |..:.:..|.:||||||.:|..|..|::..:.
 Worm   155 NELNNNCIKEIFD---LLYASNP-PKHIEEF--LDGLAYVITCITTIGYGELVCHTIAGKLVTVA 213

  Fly   195 FALIGIPFTLTVIADWG-----------RLFATAVSVFGKHMPTKPKFTNFIGKTWFYAILAVGF 248
            :.:|||..||.|:.:.|           ::||..|...||   ...|:...:.|.:   ||.|.|
 Worm   214 YGIIGIALTLYVLRNNGKITLKICNLTLKIFAICVRKCGK---KSAKYKMTVLKAF---ILLVTF 272

  Fly   249 LGVYLAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGFGDLVPK-KPNYMLLCTLYILIGLALTST 312
            .|.    ||..:.::| ::.|:|..||.|.|.:||||||.||. ..:..::|.|: .|.|:|.|.
 Worm   273 WGF----GALAIAVYE-EFVFYDALYFSFSTFSTIGFGDFVPSGHISGTIICVLH-FIDLSLISM 331

  Fly   313 IIELVRRQYATSWAKLQEL 331
            ::.||.......:.::.||
 Worm   332 VLVLVHHSMENRFMRVLEL 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	143..214	CDD:462301	22/81 (27%)
		Ion_trans_2	<267..319	CDD:462301	22/52 (42%)
twk-37	NP_491810.2	Ion_trans_2	<181..235	CDD:462301	18/55 (33%)
		Ion_trans_2	266..336	CDD:462301	28/78 (36%)