Protein Alignment CG43155 and twk-18

DIOPT Version :10

• Sequence 1: NP_572720.2
• Gene: CG43155 / 32092
• FlyBaseID: FBgn0262685
• Length: 411
• Species: Drosophila melanogaster
• Sequence 2: NP_001379714.1
• Gene: twk-18 / 181139
• WormBaseID: WBGene00006672
• Length: 461
• Species: Caenorhabditis elegans
• Alignment Length: 326
• Identity: 91/326 - (27%)
• Similarity: 141/326 - (43%)
• Gaps: 64/326 - (19%)

  Fly    69 LVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRER---FLHTI--LNNTEVHNLDELLSF 128
            |:.|..|..:|..||..:|...|.|.|      ::..:||   ...|:  :|..::.....|::.
 Worm    25 LIILVAYTLLGAWIFWMIEGENEREML------IEQQKERDELIRRTVYKINQLQIKRQRRLMTA 83

  Fly   129 ELAKYE--AAVQQAAEGGLLIV---ADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIVPVTTGG 188
            | .:|.  |.|....:..|.||   .|||.     .|:.|.::|:..||.||||||||||.|..|
 Worm    84 E-EEYNRTAKVLTTFQETLGIVPADMDKDI-----HWTFLGSIFYCMTVYTTIGYGNIVPGTGWG 142

  Fly   189 RVFCICFALIGIPFTLTVIADWGRLFA-----------TAVSVFGKHM----------------- 225
            |...|.:|.||||.|:..:...|.|||           .:..|..|.:
 Worm   143 RFATILYAFIGIPLTVLSLYCLGSLFAKGCKMLWRFFLKSTRVVSKDLSNKISEAADNIEEGTTA 207

  Fly   226 --PTKPKFTNFIGKTWFYAILAVGFLGVYLAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGFGDL 288
              |:..|..|.......:.|..:..:.|.......:|..:.::|.|....||..|:.|||||||:
 Worm   208 ITPSAEKTENNDDDLLSFPISGLLLITVIWVIFCAVLFTFLEEWDFGTSLYFTLISFTTIGFGDI 272

  Fly   289 VPKKPNYMLLCTLYILIGLALTSTIIELVRRQYATSWAKLQELSGPMAETL-----RRLGETAGT 348
            :|...::|.:..:.:||||:|.||::.|:::|       ::.|:..|.:.:     |.|.|....
 Worm   273 LPSDYDFMPIVGVLLLIGLSLVSTVMTLIQQQ-------IEALASGMKDNIDQEYARALNEARED 330

  Fly   349 G 349
            |
 Worm   331 G 331

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	143..214	CDD:462301	32/73 (44%)
		Ion_trans_2	<267..319	CDD:462301	22/51 (43%)
twk-18	NP_001379714.1	Ion_trans_2	<113..170	CDD:462301	28/56 (50%)
		Ion_trans_2	232..306	CDD:462301	25/80 (31%)