DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43155 and Kcnk15

DIOPT Version :9

Sequence 1:	NP_572720.2	Gene:	CG43155 / 32092	FlyBaseID:	FBgn0262685	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_570826.1	Gene:	Kcnk15 / 156873	RGDID:	619733	Length:	318	Species:	Rattus norvegicus

Alignment Length:	300	Identity:	87/300 - (28%)
Similarity:	121/300 - (40%)	Gaps:	60/300 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 KSALNHIGLLVSLSIYCGVGGLIFRHLERPAEVERLSHLKDIVKTHRERFLHTILNNTEVHNLDE 124
            |.:.....|::.:..|..||..:|..||..||..|    :.::...|..|......:.:.:...|
  Rat     3 KQSARTAALILCILSYLLVGAAVFDALESEAERSR----QRLLARKRGEFRRKYRFSADDYRELE 63

  Fly   125 LLSFELAKYEAAVQQAAEGGLLIVADKDFPEPYERWSILQAVFFSSTVLTTIGYGNIVPVTTGGR 189
            .|:.:...:.|..|                     |....:.:|:.||:||||||:..|.|..|:
  Rat    64 RLALQAEPHRAGRQ---------------------WRFAGSFYFAITVITTIGYGHAAPGTDSGK 107

  Fly   190 VFCICFALIGIPFTLTVIADWGR--------LFATAVSVFGKHMPTKPKFTNFIGKTWFYAILAV 246
            |||:.:||:|||.||......|.        |...|....|...| .....|.:         ..
  Rat   108 VFCMFYALLGIPLTLVTFQSLGERLNALVRCLLLAAKRCLGLRRP-HVSAENMV---------VA 162

  Fly   247 GFL--GVYLAAGAGLLLLWEDDWTFFDGFYFCFITMTTIGFGDLV--------PKKPNYMLLCTL 301
            |.|  ...||.||.....:| .||||..:|:||||:|||||||.|        .|||.|:....|
  Rat   163 GLLLCAATLALGAAAFAHFE-GWTFFHAYYYCFITLTTIGFGDFVALQRDEALQKKPPYVAFSFL 226

  Fly   302 YILIGLALTSTIIELVRRQYATSWAKLQELSGPMAETLRR 341
            |||:||.:....:.||..::      |.....|....|||
  Rat   227 YILLGLTVIGAFLNLVVLRF------LASAEAPERAALRR 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43155	NP_572720.2	Ion_trans_2	<157..214	CDD:285168	24/64 (38%)
		Ion_trans	<240..314	CDD:278921	34/83 (41%)
		Ion_trans_2	<266..319	CDD:285168	29/60 (48%)
Kcnk15	NP_570826.1	Ion_trans_2	<77..132	CDD:285168	25/75 (33%)
		Ion_trans_2	<182..243	CDD:285168	29/61 (48%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	296..318
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000030
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910